NEET Biology NEET PYQ-Biomolecule

  • question_answer
    The chemiosmotic coupling hypothesis of oxidative phosphorylation proposes that Adenosine Triphosphate (ATP) is formed because [AIPMT (S) 2008]

    A) high energy bonds are formed in mitochondrial proteins

    B) ADP is pumped out of the matrix into the Inter membrane space

    C) a proton gradient forms across the inner membrane

    D) there is a change in the permeability of the inner mitochondrial membrane toward Adenosine Diphosphate (ADP)               

    Correct Answer: C

    Solution :

    [C] The production of ATP with the help of energy liberated during oxidation of reduced coenzymes and terminal oxidation is called oxidadve phosphorylation. Peter Mitchell (1961) put forward a hypothesis known as chemiosmotic hypothesis for ATP synthesis. According to this when electrons flow from dual proton, electron carrier to a non-hydrogen carrier the \[{{H}^{+}}\]are released and expelled into the inter membrane space and thus, creates a proton gradient with higher concentration of \[{{H}^{+}}\]in the inter membranous space than the matrix. Due to proton motive force the protons flow back and energy liberated during this back flow of protons activate AT Pase present in \[{{F}_{1}}\]head to synthesize ATP.


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