JCECE Medical JCECE Medical Solved Paper-2006

  • question_answer
    Krebs cycle takes place in:

    A)  mitochondrial matrix

    B)  cytoplasm

    C)  lysosome

    D)  nucleus

    Correct Answer: A

    Solution :

     Krebs cycle (TCA or citric acid cycle) was discovered by Hans Krebs. It operates in matrix of mitochondria. The pyruvic acid formed by glycolysis enters into mitochondria and undergo oxidative decarboxylation to produce acetyl Co-A, NADH and \[\text{C}{{\text{O}}_{\text{2}}}\text{.}\]Acetyl Co-A is the  substrate entrant of Krebs cycle. In the Krebs  cycle the acetyl Co-A is completely oxidised to \[\text{C}{{\text{O}}_{\text{2}}}\text{.}\]and \[{{\text{H}}_{\text{2}}}\text{O}\text{.}\]The net product from one acetyl Co-A is 12 ATP molecules. Glycolysis takes place in cytoplasm of the cell.  Here one molecule of glucose splits into two  molecules of pyruvic acid. Lysosome contains hydrolytic enzymes. Nucleus is the control centre of cell. It contains genetic material.


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