J & K CET Medical J & K - CET Medical Solved Paper-2000

  • question_answer
    The preparation ofethylacetoacetate involves:

    A)  Reformatsky reaction

    B)  Claisen condensation

    C)  Cannizaros reaction

    D)  Wittig reaction

    Correct Answer: B

    Solution :

                    Claisen    condensation    involves    self condensation of two molecules of ester containing a-hydrogen in the presence of a strong base such as sodium ethoxide to form \[\beta -\]keto ester. \[C{{H}_{3}}-\overset{\begin{smallmatrix}  O \\  || \end{smallmatrix}}{\mathop{C}}\,----C{{H}_{2}}-\overset{\begin{smallmatrix}  O \\  || \end{smallmatrix}}{\mathop{C}}\,-O{{C}_{2}}{{H}_{5}}\]\[\xrightarrow[-{{C}_{2}}{{H}_{5}}OH]{{{C}_{2}}{{H}_{5}}ONa}\underset{\begin{smallmatrix}  ethyl\text{ }acetoaceiate \\  (\beta -ketoester) \end{smallmatrix}}{\mathop{C{{H}_{3}}-\overset{\begin{smallmatrix}  O \\  || \end{smallmatrix}}{\mathop{C}}\,-\,-\,\,\,\,\,\,C{{H}_{2}}-\overset{\begin{smallmatrix}  O \\  || \end{smallmatrix}}{\mathop{C}}\,-O{{C}_{2}}{{H}_{5}}}}\,\]


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