A) M cdk cyclin
B) G1 cdk cyclin
C) S cdk cyclin
D) Transcription factor
Correct Answer: A
Solution :
Anaphase promoting complex is a protein aggregate needed for entery into anaphase. When an unattached kinetochore is detected the bub, mad and mps 1 proteins act to block the onset of anaphase apparently by inhibiting the protein cdc 20. As cdc 20 is activated normally and in turn the anaphase promoling complex is activated. - Cyclin D is normally expressed only in G1 but the presence of a mitogen keeps the level elevated throughout and the cell cycle. - Cyclin E and its associated \[CDK\text{ }\left( cd{{k}_{2}} \right)\]initiate DNA synthesis (S phase) by phosphorylation of RB, protein and release of \[{{E}_{2}}F.\] - The transcription factor (E2F) stimulates transcription of genes whose product are used in DNA synthesis as well as genes for cyclin E, cyclin A and\[~Cd{{k}_{2}}.\]
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