DUMET Medical DUMET Medical Solved Paper-2002

  • question_answer
    The change in optical rotation (with time) of freshly prepared solution of sugar is known as:

    A)  inversion      

    B)  anomers

    C)  mutarotation  

    D)  epimers

    Correct Answer: C

    Solution :

    (i) Inversion: If the solution obtained after hydrolysis of sugar has opposite sign for optical activity, it is called inversion of sugar. e. g., \[\underset{+{{66.5}^{o}}}{\mathop{sucrose}}\,\,\,~\to \underset{+{{52.7}^{o}}}{\mathop{glucose}}\,\,\,+\underset{{{92.4}^{o}}}{\mathop{fructose}}\,\] (ii) Epimers: These are carbohydrates which differ in configuration at any carbon atom other than glycosidic carbon. (iii) Anomers: These are carbohydrates which differ in configuration at glycosidic carbon. (iv) Mutarotation: The change in optical rotation of an optically active compound in solution with time, to an equilibrium value is called mutarotation. \[\underset{+{{112}^{o}}}{\mathop{\alpha -D-glucose}}\,\underset{+{{52.7}^{o}}}{\mathop{Euilibrium}}\,\,\,mixture\]\[\underset{+{{19}^{o}}}{\mathop{\beta -D-glucose}}\,\]


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