CMC Medical CMC-Medical VELLORE Solved Paper-2015

  • question_answer
    Study the pedigree chart given below. What does it show?

    A)  Inheritance of a condition like-phenylketonuria as an autosomal recessive trait

    B)  The pedigree chart is wrong as their is not possible

    C)  Inheritance of a recessive sex-linked disease like hemophilia

    D)  Inheritance of sex-linked inborn error of metabolism like-phenylketonuria

    E)  None of the above

    Correct Answer: A

    Solution :

                    This chart shows inheritance of an autosomal recessive trait like-phenylketonuria. An autosomal recessive trait may skip a generation. It appears in case of marriage between two heterozygous individuals (Aa \[\times \] Aa = 3Aa + 1 aa), a ressive individual (aa \[\times \] aa = all aa). Phenylketonuria is an inborn autosomal, recessive metabolic a disorder in which homozygous recessive individual lacks the enzyme phenylalanine hydroxylase. The hetrozygous individuals are normal, but earners.


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