CMC Medical CMC-Medical VELLORE Solved Paper-2015

  • question_answer
    Which of the following is correct combination of reagent used and the intermediate formed in Stephen reaction?

    A)
    Reagent Intermediate
    DIBAL-H Imine

    B)
    Reagent Intermediate
    Stannous chloride Aldehyde

    C)
    Reagent Intermediate
    DIBAL-H Aldehyde

    D)
    Reagent Intermediate
    Stannous chloride Imine

    E)
    Reagent Intermediate
    None of these -

    Correct Answer: D

    Solution :

                    \[RCN+SnC{{l}_{2}}+HCl\xrightarrow{{}}RCH=NH\]\[\xrightarrow{{{H}_{3}}{{O}^{+}}}RCHO\] In this reaction, nitriles reduced to corresponding imine which upon hydrolysis give corresponding aldehyde.


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