| I. Enzyme replacement therapy. |
| II. By SIRNA approach. |
| III. Introducing bone marrow cells producing ADA into cells at early embryonic stages. |
| IV. By inserting the functional gene using retroviruses. |
| V. Periodic infusion of genetically engineered lymphocytes having functional ADA, c DNA. |
A) II, III and IV
B) III and IV
C) III and V
D) All of these
Correct Answer: B
Solution :
Permananent use of SCID caused by ADA (Adenosin Diaminase) enzyme is either by introducing bone marrow cells producing functional ADA into cells at early embryonic stages by inserting gene into genome of the cells using retro viruses.
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