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BHU PMT BHU PMT Solved Paper-2002

  • question_answer
    A person may have one gene for normal haemoglobin and one gene for sickle cell haemoglobin, this heterozygous condition is called :

    A) genome                                              

    B) anaemia

    C) sickle cell trait                   

    D) gene trait

    Correct Answer: C

    Solution :

     Sickle cell trait is a heterozygous condition in which an organism may have one gene for normal haemoglobin and other gene for sickle cell haemoglobin. Haemoglobin consist of four polypeptide chains. In sickle cell anaemia, genetic mutation takes place in P chain of Hb, and glutamic acid of P chain is replaced by valine amino acid in sickle cell anaemia. In sickle shaped anaemia RBC becomes sickle shaped.


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