AMU Medical AMU Solved Paper-2013

  • question_answer
    Which of the following carboxylic acids undergoes decarboxylation easily?

    A)  \[{{C}_{6}}{{H}_{5}}COC{{H}_{2}}COOH\]

    B)  \[{{C}_{6}}{{H}_{5}}CH\underset{\begin{smallmatrix}  | \\  OH \end{smallmatrix}}{\mathop{C}}\,OOH\]

    C)  \[{{C}_{6}}{{H}_{5}}\underset{\begin{smallmatrix}  | \\  N{{H}_{2}} \end{smallmatrix}}{\mathop{C}}\,HCOOH\]       

    D)  \[{{C}_{6}}{{H}_{5}}COCOOH\]

    Correct Answer: A

    Solution :

                     If keto group is at p-position then decarboxylation takes place simply by heating, p -keto acid is very reactive in decarboxylation reaction because it produces a highly stable carbanion.


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