AMU Medical AMU Solved Paper-2013

  • question_answer
    In TCA cycle substrate level phosphorylation takes place during the conversion of

    A)  oxaloacetic acid to citric acid

    B)  succinyl Co-A to succinic acid

    C)  succinic acid to fumaric acid

    D)  fumaric acid to malic acid

    Correct Answer: B

    Solution :

                    Tricarboxylic acid cycle or citric acid cycle or Krebs cycle takes place in matrix of mitochondria. Acetyl coenzyme-A is connecting link between cycle and EMP pathway, while oxaloacetate is acceptor molecule. Substrate level phosphorylation takes place during the conversion of succinyl Co-A to succinic acid,  Succinyl Co-A + ADP +\[{{H}_{3}}P{{O}_{4}}\xrightarrow[Co-A\,synthetase]{Succinyl}\]   succinic acid + ATP + Co-A


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