A) competitive inhibition
B) non-competitive inhibition
C) non-competitive irreversible inhibition
D) allosteric inhibition
Correct Answer: C
Solution :
In non-competitive inhibition, the inhibitor binds to an enzyme at a place other than substrate binding site. It results in destruction of enzyme activity. The substrate may combine with such an enzyme but product formation is inhibited. For example, DFP or di-isopropyl fluorophosphate (nerve gas) reacts with hydroxyl group of serine of acetylcholine-esterase. Inhibition of acetyl choline by DFP is an example of non-competitive irreversible inhibition.
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