AMU Medical AMU Solved Paper-2006

  • question_answer
    Which one of these is associated with multiple phenotypes?

    A)                  Mutation

    B)                  Pleiotropy

    C)                  Epistasis                             

    D)                  Polygenic inheritance

    Correct Answer: D

    Solution :

                     The phenotype of an individual depended on its genotype at all the relevant loci, with each allele adding a small amount. Traits that have this feature are called polygenic, ie, the genes, which are non-allelic and affect the phenotype of a single quantitative trait are called polygenes and their inheritance is called polygenic inheritance. This is proved by Nileson-Ehle in 1908 for kernel colour in wheat. The term pleiotropy refers to the situation in which a gene influences more than one trait. The \[Hb_{B}^{S}\] allelic provides a classic example of pleiotropy. In epistasis an allele of one gene obliterates the phenotypic expression of all allelic alternatives of another gene.


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