A) B-cells and T-cells
B) T-cells and spleen cells
C) spleen cells and myeloma
D) myeloma cell and B-cells
Correct Answer: D
Solution :
A hybridoma is a hybrid cell obtained by fussing a B-lymphocyte with tumour cells of the antibody forming system or of B-lymphocytes (called myelomas). The hybrid cell thus produced possess the ability to produce antibodies due to the B-lymphocyte genome and the capacity for indefinite growth in vitro due to the tumour cells involved in the fusion. The technology was developed by G Kohler and C Milstein in 1975. T cells (T lymphocytes) are a population of lymphocytes that are the principal agents of cell mediated immunity. T-cells are derived from the bone marrow but migrate to the thymus to mature hence, are known as T cells.
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