AMU Medical AMU Solved Paper-2003

  • question_answer
    Parkinsonism, which is characterized by tremors and progressive rigidity of limbs is caused by degeneration        of brain, neurons and          neuro transmitters called

    A)  dopamine                         

    B)  adrenaline

    C)  acetyl choline                  

    D)  aspartic acid

    Correct Answer: A

    Solution :

                     Parkinsons Disease (PD) is a progressive disease of the central nervous system. In this disease, there is degeneration of dopamine producing neurons in the substantia nigra and basal ganglia, resulting imbalance of neurotransmitter activity?too little dopamine and too much of acetylcholine. The person suffering from this disease shows involuntary skeletal muscle contraction called tremors. Adrenalin (epinephrin) is a hormone produced by the medulla of adrenal glands that increases heart activity, improves the power and prolongs the action of muscle and increases the rate and depth of breathing to prepare the body for ?fright?, "flight" or fight. It is also known as ?3F? hormone. Acetyl choline is an excitatory transmitter released by major portions of the CNS. Aspartic acid is a amino acid, which possesses both carboxyl (?COOH) and an amino (-NHa) group attached to same carbon.


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