question_answer

"One gene one polypeptide chain" theory was proposed by

A)                  G W Beadle and E L Tatum

B)                  Khorana and Nirenberg

C)                  Watson and Komberg

D)                  Vemon M Ingram

Correct Answer: A

Solution :

                 Genes express themselves through synthesis of enzyme was demonstrated for the first time in 1941 by G W Beadle and E L Tatum due to their discovery of biochemical  mutation in Neurospora. They proposed a concept called one gene-one enzyme hypothesis.                 Khorana and Nirenberg cracked the genetic code. They with RW Holley used in vitro system for synthesis of a polypeptide using an artificially synthesized mRNA molecule.