A) change of amino acid in -chain of haemoglobin
B) change of amino acid in -chain of haemoglobin
C) change of amino add in both and chains of haemoglobin
D) change of amino acid in either or chain of haemoglobin
Correct Answer: B
Solution :
The sixth amino acid from the amino terminal end of \[\beta \] chain of normal haemoglobin is glutamic acid while in sickle cell haemoglobin, it is valine. It results a change in confermation of the haemoglobin melecule and the RBC becomes sickle shaped.
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