AIIMS AIIMS Solved Paper-2006

  • question_answer

    Direction for: In each of the following questions a statement of Assertion is given followed by a corresponding statement of Reason just below it. Of the statements mark the correct answer as

    Assertion: A person who has received a cut and is bleeding needs to be given anti-tetanus treatment. Reason: Anti-tetanus injection provides immunity by producing antibodies for tetanus.

    A)  If both assertion and reason are true and the reason is the correct explanation of the assertion.

    B)  If both assertion and reason are true but the reason is not the correct explanation of the assertion.

    C)  If assertion is true statement but reason is false.

    D)  If both assertion and reason are false.

    Correct Answer: C

    Solution :

    Tetanus is a bacterial disease, caused by an exotoxin produced by Clostridium tetani, a motile, anaerobic, endospore forming rod. The natural reservoir of C. tetani is soil, where it is a ubiquitous resident. C. tetani normally gains access to the body through a soil-contaminated wound, typically a deep puncture. In the wound, anoxic conditions allow germination of endospores and growth of the organism. C. tetani produces a potent exotoxin, the tetanus toxin. The organism is non-invasive and so its sole method of causing disease is through the direct action of tetanus toxin on host cells. Anti-tetanus injection or antitoxin is a preparation of antibodies to tetanus. It is usually made in horses and takes part in neutralization of tetanus toxins by C. tetani.


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