AIIMS AIIMS Solved Paper-2005

  • question_answer
    Among the following the strongest nucleophile is:

    A) \[{{C}_{2}}{{H}_{5}}SH\]

    B)        \[C{{H}_{3}}CO{{O}^{-}}\]           

    C)        \[C{{H}_{3}}N{{H}_{2}}\]    

    D)        \[NCCH_{2}^{-}\]

    Correct Answer: A

    Solution :

           Nucleophile is a species which has high electron density on it and it attack on the site of less electron density. More the electron density on a species better nucleophile it is. Nucleophiles may be neutral (but with an atom with lone pairs of electron) or it can be negatively charged. \[{{C}_{2}}{{H}_{5}}SH\] is the weakest acid so it readily lose a proton to form strong conjugate base \[{{C}_{2}}{{H}_{5}}{{S}^{-}}\] which is a strong nucleophile (\[+1\] effect of \[{{C}_{2}}{{H}_{5}}\] group).


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