AFMC AFMC Solved Paper-2006

  • question_answer
    Enzymes found attached to inner membrane of mitochondria instead of matrix is/are :

    A) succinic dehydrogenase

    B) cytochrome oxidase

    C) both (a) and (b)

    D) malicdehydrogenose

    Correct Answer: C

    Solution :

    All the enzymes of Krebs cycle, fatty acid synthesis and amino acid synthesis are found in matrix but succinic dehydrogenase and cytochrome oxidase are present on inner membrane of mitochondria. The mitochondrial inner membrane contains enzymes of electron transport pathway i.e., NAD, FAD, diphosphopyredine nucleotide dehydrogenase, obiquenone or coenzyone Q10, non-heme copper and iron; ATP synthase, succinate dehydrogenase  P-hydroxybutyratede hydrogenase etc. Mitochondrial matrix contains malate dehydrogenase-isocitrate dehydrogenase, fumarase, aconitase, citrate synthase, a-keto acid dehydrogenase, p-oxidation enzymes, etc.


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