NEET Sample Paper NEET Sample Test Paper-72

  • question_answer
    Which of the following is the best method for the synthesis of ester (I) \[(M{{e}_{3}}C-COOMe)\]?

    A) \[M{{e}_{3}}C-COCl+MeOH\,\,\xrightarrow{{}}\]

    B) \[M{{e}_{3}}C-COOH+MeOH\,\,\xrightarrow{{}}\]

    C) \[{{\operatorname{Me}}_{3}}C- COOH + C{{H}_{2}}N{{H}_{2}}\,\xrightarrow{{}}\]

    D) \[{{\operatorname{Me}}_{3}}C-COCl+MeONa\,\,\xrightarrow{{}}\]

    Correct Answer: C

    Solution :

    The esterification of an alcohol with \[RCOCl\] or with RCOOH is affected by steric hindrance. Bulky group on either alcohol or acid derivatives slow down the reaction. So, the esterification with diazomethane \[(C{{H}_{2}}{{N}_{2}})\] is the best method.


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