question_answer

Consider the following statements regarding Down's syndrome

I. Trisomy \[{{Z}_{1}}\] is the cause of approximately 95% of observed Down syndromes, with 88% coming from nondisj unction in the maternal gamete and 8% coming from nondisjunction in the paternal gamete

II. It may be due to a Robertsonian translocation where the long arm of chromosome \[{{Z}_{1}}\] is attached to another chromosome, often chromosome 14

III. The down syndrome does not run in families

The correct statements include:

A)  I, II and III

B)  I and II

C)  I and III

D)  II and III