A) Metal ions loosely attached with Apoenzyme Activators
B) Non-protein organic part attached tightly to Apoenzyme - Prosthetic group
C) Non protein organic part attached loosely to Apoenzyme - Coenzyme
D) All of the above
Correct Answer: D
Solution :
A complete conjugate enzyme, consisting of an apo- enzyme and a cofactor is called holoenzyme. Cofactor is a small heat stable part of a conjugate enzyme. It may be organic or inorganic in nature. Organic cofactors are of two types, they are coenzymes and prosthetic groups: Coenzymes are easily separable organic cofactors, e.g., Nucleotides of vitamins, nicotinamide (such as NAD) and riboflavin (such as FAD) act as coenzyme of many oxidizing enzymes of the mitochondria.
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