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KVPY Sample Paper KVPY Stream-SX Model Paper-2

  • question_answer
    A mutation in one of the replication enzyme causes DNA polymerase to be unable to add nucleotides at the origin of replication, hence no daughter strands of DNA can be synthesised. Which of the following is the defective enzyme?

    A) Helicase                        

    B) Primase

    C) DNA ligase                    

    D) Topoisomerase

    Correct Answer: B

    Solution :

    [b] DNA polymerase binds to the single-stranded RNA primer and catalyses the formation of a phosphodiester bond between the free nucleotide and the preceding nucleotide, thus extending the new strand of DNA. In the event that the premise is defective, RNA primer will be absent and DNA polymerase will be unable to add nucleotides at the origin of replication.


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