question_answer

Direction (6 - 10): The search for mild, versatile, selective reagents for the operationally simple oxidation of alcohols to carbonyl compounds has long been the objectives of many research laboratories. The development of newer methods and methodologies is gaining much attention currently due to the significance of this reaction. The first advantage of pyridinium chlorochromate is that it is prepared easily and safely : the addition of chromium trioxide to 6 N hydrochloric acid furnishes the unstable chlorochromic acid : subsequent addition of pyridine at \[0{}^\circ C\] immediately gives pyridinium chlorochromate as a yellow-orange solid which is not appreciably hygroscopic.

The second advantage is that it shows a high capability to convert primary alcohols exclusively to aldehydes with great efficiency.

The utilization of the hydrogen peroxide as an oxidant for organic substrates has gained much attention in recent year, because of its environmental implications, water being the only chemical by-product; on the other hand, the water is actually used as process solvent, so the reactions are of general interest due to their potential in combinational chemistry, simple processes, easy workup, low cost and reduction in noxious waste materials.

(Reference : G. Piancateli, A Scettri, M. D'auria. Pyridinium Chlorochromate : A versatile oxidant in organic synthesis. Synthesis : International Journal of Methods in Synthetic Organic chemistry. 245-246. 1982 No. 4 : April.)

(Reference : Anil C, Ranveer, Suresh V, Ranade, Cyrus K. Mistry. Selective oxidation of alcohols to aldehydes by using hydrogen peroxide as an oxidant : A review. International Journal of Advance Research in Science and Engineering. Vol. No. 4, Special Issue (01), September 2015.)

Which of the following can be used to oxidize \[1{}^\circ \] alcohols to aldehydes?

A) \[Cr{{O}_{3}}\]                       

B) PCC 

C) \[{{H}_{2}}{{O}_{2}}\]                                  

D) All the above