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question_answer1)
Which of the following rRNAs acts as structural RNA as well as ribozyme in bacteria?
A)
23 S rRNA done
clear
B)
5.8 S rRNA done
clear
C)
5 S rRNA done
clear
D)
18 S rRNA done
clear
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question_answer2)
A molecule that can act as a genetic material must fulfill the traits given below, except
A)
It should be unstable structurally and chemically done
clear
B)
It should provide the scope for slow changes that are required for evolution done
clear
C)
It should be able to express itself in the form of 'Mendelian characters' done
clear
D)
It should be able to generate its replica done
clear
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question_answer3)
DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the
A)
Alpha strand done
clear
B)
Antistrand done
clear
C)
Template strand done
clear
D)
Coding strand done
clear
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question_answer4)
In a 3.2 kbp long piece of DNA, 820 adenine bases were found. What would be the number of cytosine bases?
A)
780 done
clear
B)
1560 done
clear
C)
740 done
clear
D)
1480 done
clear
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question_answer5)
Some of the steps of DNA finger printing are given below. Identify the correct sequence |
[a] Electrophoresis of DNA fragments |
[b] Hybridisation with DNA probe |
[c] Digestion of DNA by restriction endo- nucleases |
[d] Autoradiography |
[e] Blotting of DNA fragments to nitrocellulose membrane |
A)
c-a-b-e-d done
clear
B)
c-a-e-b-d done
clear
C)
a-e-c-b-d done
clear
D)
a-c-e-d-b. done
clear
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question_answer6)
If the sequence of bases in the coding strand of a double stranded DNA is 5-GTTCGAGTC-3-, the sequence of bases in its transcript will be
A)
5-GACUCGAAC-3- done
clear
B)
5-CAAGCUCAG-3- done
clear
C)
5-GUUCGAGUC-3- done
clear
D)
5-CUGAGCUUG-3- done
clear
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question_answer7)
The final proof for DNA as the genetic material came from the experiments of
A)
Hargobind Khorana done
clear
B)
Griffith done
clear
C)
Hershey and Chase done
clear
D)
Avery, Mcleod and McCarty done
clear
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question_answer8)
The association of histone Hi with a nucleosome indicates
A)
The DNA double helix is exposed done
clear
B)
Transcription is occurring done
clear
C)
DNA replication is occurring done
clear
D)
The DNA is condensed into a Chromatin Fibre done
clear
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question_answer9)
DNA fragments are
A)
Either positively or negatively charged depending on their size done
clear
B)
Positively charged done
clear
C)
Negatively charged done
clear
D)
Neutral done
clear
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question_answer10)
Which of the following RNAs should be most abundant in animal cell?
A)
mi-RNA done
clear
B)
r-RNA done
clear
C)
t-RNA done
clear
D)
m-RNA done
clear
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question_answer11)
During DNA replication, Okazaki fragments are used to elongate
A)
The lagging strand away from the replication fork. done
clear
B)
The leading strand towards replication fork. done
clear
C)
The lagging strand towards replication fork. done
clear
D)
The leading strand away from replication fork. done
clear
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question_answer12)
If there are 999 bases in an RNA that codes for a protein with 333 amino acids and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered?
A)
333 done
clear
B)
1 done
clear
C)
11 done
clear
D)
33 done
clear
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question_answer13)
Spliceosomes are not found in cells of
A)
Bacteria done
clear
B)
Plants done
clear
C)
Fungi done
clear
D)
Animals done
clear
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question_answer14)
What is correct about the labelling a, b and c |
|
A)
a-histone octamer, c-DNA done
clear
B)
b-Hl histone, c-histone octamer done
clear
C)
a-Hl histone, b-DNA done
clear
D)
a-histone octamer, c-Hl histone. done
clear
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question_answer15)
Match the columns and find the correct options
| I | | II |
[a] | GGG | (i) | Proline |
[b] | UUU | (ii) | Glycine |
[c] | CCC | (iii) | Arginine |
[d] | AAA | (iv) | Phenylalanine |
A)
a-v, b-ii, c-i, d-ii done
clear
B)
a-iv, b-iii, c-i, d-ii done
clear
C)
a-ii, b-iv, a-i, d-v done
clear
D)
a-i, b-ii, c-iii, d-iv done
clear
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question_answer16)
Select the correct match from the following combinations.
A)
\[{{F}_{2}}\times \]Recessive parent - Dihybrid cross done
clear
B)
T.H. Morgan - Transduction done
clear
C)
Ribozyme - Nucleic acid done
clear
D)
G. Mendel - Transformation done
clear
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question_answer17)
The experimental proof for semiconservative replication of DNA was first shown in a
A)
Bacterium done
clear
B)
Plant done
clear
C)
Fungus done
clear
D)
Virus done
clear
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question_answer18)
Select the correct match from the following combinations.
A)
Alfred Hershey and Martha Chase - TMV done
clear
B)
Matthew Meselson and F. Stahl - Pisumsativum done
clear
C)
Alee Jeffreys - Streptococcus pneumonia done
clear
D)
Francois Jacob and Jacques Monod - Lac operon done
clear
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question_answer19)
Many ribosomes may associate with a single mRNA to form multiple copies of a polypeptide simultaneously. Such strings of ribosomes are termed as
A)
Polyhedral bodies done
clear
B)
Plastidome done
clear
C)
Poly some done
clear
D)
Nucleosome done
clear
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question_answer20)
All of the following are part of an operon except
A)
structural genes done
clear
B)
an enhancer done
clear
C)
an operator done
clear
D)
an promoter done
clear
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question_answer21)
AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?
A)
UGGTUTCGCAT done
clear
B)
ACCUAUGCGAU done
clear
C)
AGGUAUCGCAU done
clear
D)
UCCAUAGCGUA done
clear
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question_answer22)
Match column-I to the column-II and select the option having correct matching
| Column - I | | Column - II |
[a] | Bacteriophage\[\lambda \] | (i) | 5386 nucleotide |
[b] | E.coli | (ii) | \[3.3\times {{10}^{9}}bp\] |
[c] | Human genome | (iii) | \[4.6\times {{10}^{6}}\,bp\] |
[d] | \[\phi \times 174\] | (iv) | 48502 bp |
A)
A - (iv), B - (iii), C - (ii), D - (i) done
clear
B)
A - (iii), B - (ii), C - (i), D - (iv) done
clear
C)
A - (iv), B - (iii), C - (i), D - (ii) done
clear
D)
A - (iv), B - (i), C - (ii), D - (iii) done
clear
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question_answer23)
Which of the following correctly assigns the codons for glycine?
A)
GGG, GGC, GGA done
clear
B)
AAA, AAG, AAC done
clear
C)
AUG, AUA, AUC done
clear
D)
CCC, CCG, CGA done
clear
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question_answer24)
Select the wrong pair
A)
RNA polymerase I - Sn RNA 5S rRNA, r-RNA done
clear
B)
RNA polymerase I - r-RNA done
clear
C)
RNA polymerase II - hnRNA done
clear
D)
RNA polymerase III - tRNA done
clear
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question_answer25)
In the diagram given figure of Lac operon
A)
i - Represser, z - P-galactosidase, y-Permease, a- Transacetylase done
clear
B)
i - Inhibitor, z - Represser, y - Transacetylase, a - Permease done
clear
C)
i - Inducer, z - P-galactosidase, y - Permease, a - Represser done
clear
D)
i - P-galactosidase, z - Represser, y- Permease, a - Transacetylase done
clear
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question_answer26)
Directions : (26 - 30) |
In the following questions a statement of assertion followed by a statement of reason is given. |
Choose the correct answer out of the following choices : |
|
Assertion: Euchromatin is transcriptionally active chromatin. |
Reason: Heterochromatin is transcriptionally inactive chromatin. |
A)
Assertion and reason both are correct statements and reason is correct explanation for assertion. done
clear
B)
Assertion and reason both are correct statements but reason is not correct explanation for assertion. done
clear
C)
Assertion is correct statement but reason is wrong statement. done
clear
D)
Assertion is wrong statement but reason is correct statement. done
clear
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question_answer27)
Assertion: S - strain of Streptococcus pneumonlae is virulent in nature. |
Reason: R - strain of Streptococcus pneumoniae is non - virulent in nature. |
A)
Assertion and reason both are correct statements and reason is correct explanation for assertion. done
clear
B)
Assertion and reason both are correct statements but reason is not correct explanation for assertion. done
clear
C)
Assertion is correct statement but reason is wrong statement. done
clear
D)
Assertion is wrong statement but reason is correct statement. done
clear
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question_answer28)
Assertion: DNA and RNA are able to generate their replica inside the cell. |
Reason: Protein also show replication power inside the cell. |
A)
Assertion and reason both are correct statements and reason is correct explanation for assertion. done
clear
B)
Assertion and reason both are correct statements but reason is not correct explanation for assertion. done
clear
C)
Assertion is correct statement but reason is wrong statement. done
clear
D)
Assertion is wrong statement but reason is correct statement. done
clear
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question_answer29)
Assertion: Leading strand of DNA grows continuously during replication. |
Reason: Lagging strand of DNA grows discontinuously during replication. |
A)
Assertion and reason both are correct statements and reason is correct explanation for assertion. done
clear
B)
Assertion and reason both are correct statements but reason is not correct explanation for assertion. done
clear
C)
Assertion is correct statement but reason is wrong statement. done
clear
D)
Assertion is wrong statement but reason is correct statement. done
clear
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question_answer30)
Assertion: Prokaryotes have monocistronic mRNA in nature. |
Reason: Eukaryotes cells also have monocistronic mRNA in nature. |
A)
Assertion and reason both are correct statements and reason is correct explanation for assertion. done
clear
B)
Assertion and reason both are correct statements but reason is not correct explanation for assertion. done
clear
C)
Assertion is correct statement but reason is wrong statement. done
clear
D)
Assertion is wrong statement but reason is correct statement. done
clear
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question_answer31)
Directions : (31 - 35) |
Read the passage given below and answer the following questions. |
Regulation of gene expression refers to a very broad term that may occur at various levels. Considering that gene expression results in the formation of a polypeptide, it can be regulated at several levels. In eukaryotes, the regulation could be exerted at |
(i) transcriptional level i.e., formation of primary transcript, |
(ii) processing level i.e., regulation of splicing, |
(iii) transport of mRNA from nucleus to the cytoplasm, |
(iv) translational level. |
The genes in a cell are expressed to perform a particular function(s). For example, if an enzyme called beta-galactosidase is synthesised by E. coli, it is used to catalyse the hydrolysis of a disaccharide, lactose into galactose and glucose; the bacteria use them as a source of energy. Hence, if the bacteria do not have lactose around them to be utilised for energy source, they would no longer require the synthesis of the enzyme beta-galactosidase. Therefore, in simple terms, it is the metabolic, physiological or environmental conditions that regulate the expression of genes. The development and differentiation of embryo into adult organisms are also a result of the coordinated regulation of expression of several sets of genes. In prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression. In a transcription unit, the activity of RNA polymerase at a given promoter is in turn regulated by interaction with accessory proteins, which affect its ability to recognise start sites. These regulatory proteins can act both positively (activators) and negatively (repressers). The accessibility of promoter regions of prokaryotic DNA is in many cases regulated by the interaction of proteins with sequences termed operators. The operator region is adjacent to the promoter elements in most operons and in most cases the sequences of the operator bind a represser protein. Each operon has its specific operator and specific represser, e.g., lac operator is present only in the lac operon and it interacts specifically with lac represser only. |
Gene expression in the cell results in the formation of
A)
Polysaccharide done
clear
B)
Polypeptide done
clear
C)
Glucose and fructose done
clear
D)
Deoxyribose and ribose done
clear
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question_answer32)
Beta - galactosidase in E. coli is used to catalyse the hydrolysis of
A)
Monosaccharide done
clear
B)
Polysaccharide done
clear
C)
Disaccharide done
clear
D)
Trisaccharide done
clear
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question_answer33)
Nature of a represser in lac operon is
A)
Lipid only done
clear
B)
Polysaccharide only done
clear
C)
Nucleic acid only done
clear
D)
Protein only done
clear
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question_answer34)
Regulatory proteins in the gene expression can act as
A)
Activators only done
clear
B)
Repressers only done
clear
C)
Both of the above done
clear
D)
None of the above done
clear
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question_answer35)
Lac operon is stand for
A)
Lactic acid operon done
clear
B)
Leucine operon done
clear
C)
Lactose operon done
clear
D)
Lysine operon done
clear
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