-
question_answer1)
Sexual reproduction in which DNA of bacteria is transferred to another by the help of bacteriophage is
A)
Transformation done
clear
B)
Transduction done
clear
C)
Transcription done
clear
D)
Configuration done
clear
View Solution play_arrow
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question_answer2)
The transfer of genetic material from one bacterium to another by virus is called
A)
Transduction done
clear
B)
Translation done
clear
C)
Conjugation done
clear
D)
Transformation done
clear
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question_answer3)
One of these is not prepared directly from DNA
A)
Another DNA done
clear
B)
mRNA done
clear
C)
Protein done
clear
D)
tRNA done
clear
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question_answer4)
What happened when heat killed S cells along with live R cells were injected into mice?
A)
Mice survived and showed live S cells done
clear
B)
Mice died and showed, S cells done
clear
C)
Mice survived and showed live R cells done
clear
D)
Mice died and showed dead S cells done
clear
View Solution play_arrow
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question_answer5)
Reverse transcription is
A)
DNA synthesized from RNA done
clear
B)
RNA synthesized from DNA done
clear
C)
DNA synthesized from 3' to 5' end done
clear
D)
DNA synthesized from 5' to 3' end done
clear
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question_answer6)
Unwinding of DNA is done by
A)
Topoisomerase done
clear
B)
Exonuclease done
clear
C)
Helicase done
clear
D)
Telophase done
clear
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question_answer7)
What is shown in the following figure? |
|
A)
One Polynucleotide chains done
clear
B)
Two Polynucleotide chains done
clear
C)
Three Polynucleotide chains done
clear
D)
Four Polynucleotide chains done
clear
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question_answer8)
DNA helix model was given by
A)
Watson and Crick done
clear
B)
Knoll and Ruska done
clear
C)
Khorana done
clear
D)
Priestley done
clear
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question_answer9)
During the replication of a bacterial chromosome, DNA synthesis starts from the replication origin site and
A)
Moves in bi-directional way done
clear
B)
RNA primers are in involved done
clear
C)
Is facilitated by telomerase done
clear
D)
Moves in one direction of site done
clear
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question_answer10)
DNA repair is carried out by
A)
DNA ligase done
clear
B)
DNA polymerase done
clear
C)
DNA polymerase II done
clear
D)
DNA polymerase I done
clear
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question_answer11)
A double stranded DNA having 100,000 bp will have a length of
A)
10,000 nm done
clear
B)
101 nm done
clear
C)
\[3.4\times {{10}^{4}}\,nm\] done
clear
D)
200,000 nm done
clear
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question_answer12)
Which one of the following correctly represents the manner of replication of DNA?
A)
B)
C)
D)
View Solution play_arrow
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question_answer13)
The total number of nitrogenous bases in human genome is estimated to be about
A)
3.5 million done
clear
B)
35 thousand done
clear
C)
35 million done
clear
D)
3.1 billion done
clear
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question_answer14)
DNA repairing is done by
A)
Ligase done
clear
B)
DNA polymerase I done
clear
C)
DNA polymerase II done
clear
D)
Both [a] and [b] done
clear
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question_answer15)
A ribotide or ribonucleotide is made up of
A)
Adenine + Deoxyribose + Phosphate done
clear
B)
Uracil + Ribose + Phosphate done
clear
C)
Thymine = Ribose + Phosphate done
clear
D)
Uracil + Deoxyribose + Phosphate done
clear
View Solution play_arrow
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question_answer16)
The double helix model of Watson and Crick is known as :
A)
C DNA done
clear
B)
Z DNA done
clear
C)
D DNA done
clear
D)
B DNA done
clear
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question_answer17)
Viral genome incorporated and integrated with bacterial genome is referred to as :
A)
Prophage done
clear
B)
RNA done
clear
C)
DNA done
clear
D)
Both [b] and [c] done
clear
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question_answer18)
DNA fragments are joined in a correct sequence by
A)
DNA polymerase I done
clear
B)
DNA ligase done
clear
C)
RNA polymerase done
clear
D)
Helicase done
clear
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question_answer19)
Which one of the following is correctly matched?
A)
Frederick Griffith - Discovered the phenomenon of transformation done
clear
B)
Linus Pauling - Isolated DNA for the first time done
clear
C)
Francis Crick - Proposed one gene one polypeptide hypothesis done
clear
D)
George Beadle - Proposed concept of inborn errors done
clear
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question_answer20)
A nucleosome is a portion of the chromonema or chromotene containing:
A)
Only histones done
clear
B)
Both DNA and histones done
clear
C)
Only DNA done
clear
D)
Both DNA and RNA done
clear
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question_answer21)
DNA is methylated at :
A)
A-residue done
clear
B)
G-residue done
clear
C)
T-residue done
clear
D)
C-residue done
clear
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question_answer22)
Degeneration of DNA after heating can be studied by comparing :
A)
A : T ratio done
clear
B)
G : C ratio done
clear
C)
Sugar : Phosphate ratio done
clear
D)
Number of nucleotides done
clear
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question_answer23)
DNA in eukaryotes is a double helix and:
A)
Complementary and parallel done
clear
B)
Complementary and antiparallel done
clear
C)
Without supercoils done
clear
D)
Always circular done
clear
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question_answer24)
DNA multiplication is called :
A)
Translation done
clear
B)
Replication done
clear
C)
Transduction done
clear
D)
Transcription done
clear
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question_answer25)
DNA length per turn of helix is :
A)
3.8 A done
clear
B)
3.4 A done
clear
C)
6.8 A done
clear
D)
34 A done
clear
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question_answer26)
The following ratio is generally constant for a given species :
A)
A+G/C+T done
clear
B)
T+C/G+A done
clear
C)
G+C/A+T done
clear
D)
A+C/T+G done
clear
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question_answer27)
RNA and DNA are similar in :
A)
Having similar sugars done
clear
B)
Having similar pyrimidine bases done
clear
C)
Being capable to replicate done
clear
D)
Being polymers of nucleotide done
clear
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question_answer28)
What is shown in the following figure? |
|
A)
Single stranded polynucleotide chain done
clear
B)
Double stranded polynucleoside chain done
clear
C)
One stranded polynucleoside chain done
clear
D)
Double stranded polynucleotide chain done
clear
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question_answer29)
Which one of the following makes use of RNA as a template to synthesize DNA?
A)
Reverse transcriptase done
clear
B)
DNA dependent RNA polymerase done
clear
C)
DNA polymerase done
clear
D)
RNA polymerase done
clear
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question_answer30)
Which of the following first suggest the conservative model of DNA replication?
A)
Cairns done
clear
B)
Messelson and Stahl done
clear
C)
Watson and Crick done
clear
D)
Taylor done
clear
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question_answer31)
Genetic material of retrovirus is :
A)
DNA done
clear
B)
RNA done
clear
C)
Both [a] and [b] done
clear
D)
None of these done
clear
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question_answer32)
E. coli about to replicate was placed in a medium containing radioactive thymidine for five minutes Then it was made to replicate in a normal medium. Which of the following observation will be correct
A)
Both the strands of DNA will be radioactive done
clear
B)
One strand radioactive done
clear
C)
Each strand half radioactive done
clear
D)
None is radioactive done
clear
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question_answer33)
How many base pairs are present in B - DNA?
A)
12 done
clear
B)
11 done
clear
C)
10 done
clear
D)
9 done
clear
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question_answer34)
Isoiopes used for proving semiconservative replication of DNA are
A)
\[{{N}^{14}}\]and \[{{P}^{31}}\] done
clear
B)
\[{{N}^{14}}\]and \[{{N}^{15}}\] done
clear
C)
\[{{N}^{14}}\]and \[{{C}^{14}}\] done
clear
D)
\[{{C}^{14}}\] and\[{{P}^{31}}\] done
clear
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question_answer35)
Z - DNA in eukaryotes is
A)
Right handed and has about 12 bases per turn done
clear
B)
Left handed and has about 12 bases per turn done
clear
C)
Right handed and has about 10 bases per turn done
clear
D)
Left handed and has about 10 bases per turn done
clear
View Solution play_arrow
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question_answer36)
Consider the parts labelled in 1 and 2 respectively in the following diagram of DNA double helix and find out the correct sequences : |
|
A)
1 - Base pairs; 2 - Sugar phosphate backbone done
clear
B)
1 - Base pairs; 2 - Sugar adenine phosphate backbone done
clear
C)
1 - Base pairs; 2 - Sugar thymine phosphate backbone done
clear
D)
1 - Base pairs; 2 - Sugar uracil phosphate backbone done
clear
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question_answer37)
Nucleotide arrangement in DNA can be seen by:
A)
X-ray crystallograp done
clear
B)
Electron microscope done
clear
C)
Ultra centrifuge done
clear
D)
Transcriptase done
clear
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question_answer38)
Which particular process was used by Meselson and Franklin in order to study the semi-conservatireplication of DNA:
A)
Centrifugation done
clear
B)
Chromatography done
clear
C)
Density gradient centrifugation done
clear
D)
Buoyant density centrifugation done
clear
View Solution play_arrow
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question_answer39)
DNA was first discovered by :
A)
J.D. Watson done
clear
B)
Francis Crick done
clear
C)
Friedrich-Miescher done
clear
D)
H.G. Khurana done
clear
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question_answer40)
Which of the following is purely inactive?
A)
Euchromatin done
clear
B)
Heterochromatin done
clear
C)
Both [a] and [b] done
clear
D)
None of these done
clear
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question_answer41)
DNA replication includes:
A)
DNA ligase done
clear
B)
DNA polymerase and ligase done
clear
C)
RNA polymeras done
clear
D)
All of the above done
clear
View Solution play_arrow
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question_answer42)
During DNA replication in prokaryotes DNA is anchored to:
A)
Chromosome done
clear
B)
Mesosome done
clear
C)
Nucleolus done
clear
D)
Ribosome done
clear
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question_answer43)
Stain used by Feulgen to stain DNA is :
A)
Janus green done
clear
B)
Basic fuschin done
clear
C)
Crystal violet done
clear
D)
Methylene blue done
clear
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question_answer44)
In microbial genetics which one is referred to as 'Griffith Effect'?
A)
Conjugation done
clear
B)
Transduction done
clear
C)
Transformation done
clear
D)
Sexudation done
clear
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question_answer45)
If percentage of cytosine is 18%, then percentage of adenine will be :
A)
32% done
clear
B)
64% done
clear
C)
36% done
clear
D)
23% done
clear
View Solution play_arrow
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question_answer46)
DNA nucleotides are attached by
A)
Hydrogen bond done
clear
B)
Covalent bond done
clear
C)
Vander Waals bond done
clear
D)
Electrovalent bond done
clear
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question_answer47)
Consider the parts labelled in 1, 2, 3 and 4 respectively in the following diagram of Nucleosome and find out the correct sequences: |
|
A)
1 - DNA; 2 - H2 histone; 3 - Histone octamer; 4 - Core of histone molecules done
clear
B)
1 - DNA; 2 - H3 histone; 3 - Histone octamer; 4 - Core of histone molecules done
clear
C)
1 - DNA; 2 - H4 histone; 3 - Histone octamer; 4 - Core of histone molecules done
clear
D)
1 - DNA; 2 - H1 histone; 3 - Histone octamer; 4 - Core of histone molecules done
clear
View Solution play_arrow
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question_answer48)
Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a triplet?
A)
Nirenberg and Mathae done
clear
B)
Hershey and Chase done
clear
C)
Morgan and Sturtevant done
clear
D)
Beadle and Tatum done
clear
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question_answer49)
The coding segment of eukaryotic DNA is :
A)
Exon done
clear
B)
Replicon done
clear
C)
Intron done
clear
D)
Muton done
clear
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question_answer50)
Okazaki is known for his contribution to the understanding of :
A)
Transcription done
clear
B)
Translation done
clear
C)
DNA replication done
clear
D)
Mutation done
clear
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question_answer51)
The beginning of understanding genetic transformation in bacteria was made'-
A)
Frederick Griffith done
clear
B)
Hershey and Chase done
clear
C)
Watson and Crick done
clear
D)
T.H. Morgan done
clear
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question_answer52)
DNA gyrase, the enzyme that participates in the process of DNA replication is a type of :
A)
DNA topoisomerase done
clear
B)
Reverse transcriptase done
clear
C)
DNA ligase done
clear
D)
DNA polymerase done
clear
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question_answer53)
Compare the statements A and B. |
Statement A: Synthesis of DNA takes place in the S-phase of interphase. |
Statement B: Every chromosome, during metaphase, has two chromatids and one centromere. |
Choose the correct description : |
A)
Statement A is wrong and B is correct done
clear
B)
Statement A is correct and B is wrong done
clear
C)
Both the statements A and B are correct and A is the reason for B done
clear
D)
Both the statements A and B are correct and A is not the reason for B. done
clear
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question_answer54)
The process of copying genetic information from one strand of the DNA into RNA is termed as :
A)
Translation done
clear
B)
Transamination done
clear
C)
Replication done
clear
D)
Transcription done
clear
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question_answer55)
During Meselson and Stahl's experiments, heavy DNA was distinguished from normal DNA by centrifugation in
A)
CsOH gradient done
clear
B)
\[^{14}N{{H}_{4}}Cl\] done
clear
C)
\[^{15}N{{H}_{4}}Cl\] done
clear
D)
CsCl done
clear
View Solution play_arrow
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question_answer56)
A typical nucleosome gradient in eukaryotic cell contains:
A)
100 bp of DNA helix done
clear
B)
200 bp of DNA helix done
clear
C)
300 bp of DNA helix done
clear
D)
400 bp of DNA helix done
clear
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question_answer57)
A mixture containing DNA fragments, A, B C and D with molecular weights of A+B=C, \[A>B\] and \[D>C\], was subjected to agarose gel electrophoresis. The positions of these fragments from cathode to anode sides of the gel would be:
A)
B, A, C, D done
clear
B)
A, B, C, D done
clear
C)
C, B, A, D done
clear
D)
B, A, D, C done
clear
View Solution play_arrow
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question_answer58)
Which of the following DNA sequences qualifies to be designated as a palindrome?
A)
5' - GACCAG - 3' in one strand done
clear
B)
3' - GACCAG - 5' in one strand done
clear
C)
5' - GACCAG - 3' 3' - CTGGTC - 5' done
clear
D)
5 - AGCGCT - 3' 3' - TCGCGA - 5' done
clear
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question_answer59)
If the total amount of adenine and thymine in a double standard DNA is 45%, the amount of guanine in DNA will be:
A)
22.5% done
clear
B)
27.5% done
clear
C)
45% done
clear
D)
55% done
clear
View Solution play_arrow
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question_answer60)
Purines possess nitrogen at
A)
1, 2, 4 and 6 position done
clear
B)
1, 3, 5 and 7 position done
clear
C)
1, 3, 7 and 9 position done
clear
D)
1, 2, 6 and 8 position done
clear
View Solution play_arrow
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question_answer61)
In a DNA molecule distance between two bases is:
A)
\[2nm/20\overset{O}{\mathop{A}}\,\] done
clear
B)
\[0.2nm/2\overset{O}{\mathop{A}}\,\] done
clear
C)
\[3.4nm/34\overset{O}{\mathop{A}}\,\] done
clear
D)
\[0.34nm/3.4\overset{O}{\mathop{A}}\,\] done
clear
View Solution play_arrow
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question_answer62)
The enzyme needed in biological systems for joining two molecules is called:
A)
Lyases done
clear
B)
Diastases done
clear
C)
Polymerase done
clear
D)
Hydrolase done
clear
View Solution play_arrow
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question_answer63)
Which of the following is structural subunit of DNA?
A)
Protein done
clear
B)
Carbohydrate done
clear
C)
RNA done
clear
D)
Nucleotides done
clear
View Solution play_arrow
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question_answer64)
Nitrogenous base present in DNA:
A)
Adenine, guanine, cytosine, thymine done
clear
B)
Adenine, guanine, cytosine, uracil done
clear
C)
Adenine, thymine, uracil done
clear
D)
Guanine, uracil done
clear
View Solution play_arrow
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question_answer65)
What is shown in the following figure? |
|
A)
Frederick Griffith - experiment done
clear
B)
The Hershey - Chase experiment done
clear
C)
Taylor - experiment done
clear
D)
Avery MacLeod and Maclyn - experiment done
clear
View Solution play_arrow
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question_answer66)
The Hershey - Chase experiment In polynucleotide chain, nucleoside formed through N-glycosidic linkage by joining
A)
Phosphate group with Nitrogenous base done
clear
B)
Nitrogenous base with Nitrogenous base done
clear
C)
Nitrogenous base with Pentose sugar done
clear
D)
Pentose sugar with Phosphate group done
clear
View Solution play_arrow
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question_answer67)
The enzyme responsible for reverse transcription is:
A)
RNA polymerase done
clear
B)
DNA polymerase done
clear
C)
Reverse transcriptase done
clear
D)
Transcriptase done
clear
View Solution play_arrow
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question_answer68)
The central dogma of protein synthesis is :
A)
Protein \[\to RNA\to DNA\] done
clear
B)
Protein\[\to DNA\to RNA\] done
clear
C)
\[RNA\to DNA\to \Pr otein\] done
clear
D)
\[DNA\to RNA\to \Pr otein\] done
clear
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question_answer69)
What is shown in the following figure? |
|
A)
The Hershey - Chase experiment done
clear
B)
Taylor - experiment done
clear
C)
Avery MacLeod and Maclyn -experiment done
clear
D)
Meselson and Stahl's Experiment done
clear
View Solution play_arrow
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question_answer70)
A - DNA is
A)
left handed helix with 12 nucleotide pairs per turn done
clear
B)
right handed helix with 11 nucleotide pairs per turn done
clear
C)
right handed helix with 12 nucleotide pairs per turn done
clear
D)
left handed helix with 11 nucleotide pairs per turn done
clear
View Solution play_arrow
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question_answer71)
Read the following statements and choose the correct option |
[A] Nitrogenous base is linked to the pentose sugar through a N-glycosidic linkage. |
[B] Phosphate group is linked to 5' - OH of a nucleoside through phosphoester linkage |
[C] Two nucleosides are linked through 3' - 5' N-glycosidic linkage |
[D] Negatively charged DNA is wrapped around positively charged histone octamer to form nucleosome |
[E] The chromatin that is more densely packed and stains dark is called euchromatin |
A)
A, B and C alone are wrong done
clear
B)
D alone is wrong done
clear
C)
C and E alone are wrong done
clear
D)
A alone is wrong done
clear
View Solution play_arrow
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question_answer72)
Match the column I with column II and choose the correct option
| Column - I | | Column - II |
[a] | Incomplete dominance | (i) | Hershey and Chase |
[b] | Linkage | (ii) | Antitrhinum sp. |
[c] | Transforming principle | (iii) | Griffith |
[d] | Proved that DNA is the genetic material | (iv) | Morgan |
A)
A-i; B-iv; C-iii; D-ii done
clear
B)
A-iv; B-ii; C-iii; D-i done
clear
C)
A-ii; B-iii; C-iv; D-i done
clear
D)
A-ii; B-iv; C-iii; D-i done
clear
View Solution play_arrow
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question_answer73)
The enzyme required to catalyze the polymerization of deoxynucleotide is
A)
DNA ligase done
clear
B)
DNA polymerase done
clear
C)
P-galactosidase done
clear
D)
transacetylase done
clear
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question_answer74)
Okazaki fragments during the formation of lagging strand are
A)
large DNA segments having promoter, initiation, coding and terminator regions done
clear
B)
short segments of replicated DNA formed from DNA template with polarity \[5'\to 3'\] done
clear
C)
additional nucleotides added to the ends of RNA done
clear
D)
short segments of wrong bases introduced during replication done
clear
View Solution play_arrow
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question_answer75)
Number of histone proteins in each nucleosome core is
A)
8 done
clear
B)
10 done
clear
C)
12 done
clear
D)
14 done
clear
View Solution play_arrow
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question_answer76)
DNA parts which can switch their positions are
A)
cistrons done
clear
B)
transposons done
clear
C)
introns done
clear
D)
none of these done
clear
View Solution play_arrow
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question_answer77)
DNAase is
A)
a hormone done
clear
B)
an enzyme done
clear
C)
a catalyst done
clear
D)
a carbohydrate done
clear
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question_answer78)
Which is the first evolved genetical material on this earth
A)
mRNA done
clear
B)
tRNA done
clear
C)
rRNA done
clear
D)
DNA done
clear
View Solution play_arrow
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question_answer79)
The double helix of DNA is made of polynucleotide chains wherein backbone constituted by sugar- phosphate and the bases projected
A)
inside done
clear
B)
outside done
clear
C)
one base inside and the other outside done
clear
D)
bases remain in line of sugar-phosphate. done
clear
View Solution play_arrow
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question_answer80)
In eukaryotic genes, coding sequences are called
A)
introns done
clear
B)
exons done
clear
C)
regulatory sequence done
clear
D)
repetitive DNA done
clear
View Solution play_arrow
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question_answer81)
If the sequence of bases in the coding strand of a double stranded DNA is 5'-GTTCGAGTC-3', the sequence of bases in its transcript will be
A)
5'-GACUCGAAC-3' done
clear
B)
5'-CAAGCUCAG-3' done
clear
C)
5'-GUUCGUGUC-3' done
clear
D)
5'-CUGAGCUUG-3' done
clear
View Solution play_arrow
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question_answer82)
The structure of E. coli chromosomal DNA is
A)
double stranded, right, handed and circular done
clear
B)
single stranded, right handed and circular done
clear
C)
double stranded, left handed and linear done
clear
D)
double stranded, left handed and circular done
clear
View Solution play_arrow
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question_answer83)
Who gave semi-conservative mode of DNA replication for the first time in E. coli with the help of 15N heavy nitrogen isotope?
A)
Watson and Crick done
clear
B)
Kornberg and Ochoa done
clear
C)
Meselson and Stahl done
clear
D)
Luria and Delbruck done
clear
View Solution play_arrow
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question_answer84)
What will be the number of histone molecules in a chromatin fibre of a eukaryotic cell having 50 nucleosomes?
A)
400 done
clear
B)
450 done
clear
C)
500 done
clear
D)
1000 done
clear
View Solution play_arrow
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question_answer85)
Who gave the concept that for a double stranded DNA the ratio between A = T and G s C are equal and constant?
A)
Watson and Crick done
clear
B)
Wilkins and Franklin done
clear
C)
Wilkins and Chargaff done
clear
D)
Chargaff done
clear
View Solution play_arrow
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question_answer86)
A stretch of DNA consisting of 10-20 bases is most appropriately be called as
A)
polynucleotide done
clear
B)
nucleotides done
clear
C)
nucleosides done
clear
D)
oligonucleotide done
clear
View Solution play_arrow
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question_answer87)
Choose the right one which denotes genetic diversity.
A)
Chromosomes \[\to \] Nucleotides \[\to \] Genes \[\to \] Individuals \[\to \] Populations done
clear
B)
Population \[\to \] Individuals \[\to \]Chromosomes \[\to \] Nucleotides\[\to \] Genes done
clear
C)
Nucleotides \[\to \] Genes \[\to \] Chromosomes \[\to \]Individuals \[\to \] Populations done
clear
D)
Nucleotides \[\to \] Genes \[\to \] Chromosomes \[\to \]Individuals \[\to \] Populations done
clear
View Solution play_arrow
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question_answer88)
The sequence of nitrogenous bases in one strand of DNA are 3' TAC GCG ACG 5'. The complementary DNA strand should have
A)
5' AUG CGC TGC 3' done
clear
B)
3' ATG CGC TGC 5' done
clear
C)
5' UAC GCG ACG 3' done
clear
D)
5' ATG CGC TGC 3' done
clear
View Solution play_arrow
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question_answer89)
Identify the wrong statement about DNA.
A)
The length of DNA is defined as the number of base pairs present in it. done
clear
B)
Cytosine is common to both DNA and RNA. done
clear
C)
In a nucleotide, the nitrogenous base is linked to a phosphate group. done
clear
D)
Thymine is chemically 5-methyl uracil. done
clear
View Solution play_arrow
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question_answer90)
Which property among these listed below is not a criterion for a molecule to act as a genetic material
A)
Generate its replica done
clear
B)
Chemically and structurally stable done
clear
C)
Mutate slowly to facilitate evolution done
clear
D)
Destroy itself after every cell cycle. done
clear
View Solution play_arrow
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question_answer91)
Match column I with column II and choose the correct option.
| Column - I (Scientist) | | Column - II (Concept) |
I. | Taylor and colleagues | [A] | Lac operon |
II. | Hershey &, Chase | [B] | DNA replicates semi-conservatively |
III. | Grififfith | [C] | Transforming principle |
IV. | Jacob & Monod | [D] | DNA is the genetic material |
| | [E] | Transcription |
A)
I-B, II-E, III-A, IV-C done
clear
B)
I-C, II-D, III-B, IV-A done
clear
C)
I-B, II-D, III-C, IV-A done
clear
D)
I-A, II-E, III-D, IV-B done
clear
View Solution play_arrow
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question_answer92)
Consider the parts labelled in 1, 2, 3 and 4 respectively in the following diagram of Replicating Fork and find out the correct sequences : |
|
A)
1 - Coding DNA; 2 - Discontinuous synthesis; 3 - Newly synthesized strands; 4 - Continuous synthesis done
clear
B)
1 - Template DNA; 2 - Continuous synthesis; 3 - Newly synthesized strands; 4 - Continuous synthesis done
clear
C)
1 - Template DNA; 2 - Discontinuous synthesis; 3 - Newly synthesized strands; 4 - Discontinuous synthesis done
clear
D)
1 - Template DNA; 2 - Discontinuous synthesis; 3 - Newly synthesized strands; 4 - Continuous synthesis done
clear
View Solution play_arrow
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question_answer93)
Retroviruses are implicated as a cause for cancer in humans because
A)
Carry gene for reverse transcriptase done
clear
B)
May carry cellular oncogenes in their genome done
clear
C)
May carry viral oncogenes in their genome done
clear
D)
Carry single stranded RNA as their genetic material done
clear
View Solution play_arrow
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question_answer94)
RNA retroviruses have a special enzyme that
A)
Transcribes viral RNA to c-DNA done
clear
B)
Disintegrates host's DNA done
clear
C)
Translates host's DNA done
clear
D)
Polymerises hosts DNA done
clear
View Solution play_arrow
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question_answer95)
Genes that are involved in turning on or off the transcription of a set of structural genes are called
A)
Polymorphic genes done
clear
B)
Regulator genes done
clear
C)
Redundant genes done
clear
D)
Operator genes done
clear
View Solution play_arrow
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question_answer96)
Our muscle cells are different form our nerve cells mainly because
A)
They express different genes done
clear
B)
They contain different genes done
clear
C)
They use different genetic codes done
clear
D)
They have unique ribosomes done
clear
View Solution play_arrow
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question_answer97)
In 'lac Operon' represser protein attaches to
A)
Operator done
clear
B)
Promoter done
clear
C)
Regulator done
clear
D)
b-galactosidase done
clear
View Solution play_arrow
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question_answer98)
During splicing the exons are joined and the enzymes which catalyzes this reaction is
A)
RNA ligase done
clear
B)
RNA catalase done
clear
C)
RNA polymerase done
clear
D)
RNA permease done
clear
View Solution play_arrow
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question_answer99)
What is shown in the following figure ? |
|
A)
Schematic structure of a transcription unit done
clear
B)
Schematic structure of a replication unit done
clear
C)
Schematic structure of a translation unit done
clear
D)
Schematic structure of a protein synthesis unit done
clear
View Solution play_arrow
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question_answer100)
A polysome is formed by
A)
A cluster of ribosomes done
clear
B)
Many ribosomes attached to a m RNA done
clear
C)
A cluster of ribosomal sub units done
clear
D)
Many mRNAs being attached to a ribosome done
clear
View Solution play_arrow
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question_answer101)
During protein synthesis the anticodon on tRNA pairs with
A)
Codon on tRNA done
clear
B)
Codon on mRNA done
clear
C)
Ribosome unit done
clear
D)
Codon on rRNA done
clear
View Solution play_arrow
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question_answer102)
One of these is not associated with termination of protein synthesis
A)
UAA done
clear
B)
UAG done
clear
C)
UGA done
clear
D)
AUG done
clear
View Solution play_arrow
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question_answer103)
RNA polymerase I of an eukaryotic cell catalyzes
A)
Elongation in transcription done
clear
B)
rRNA synthesis done
clear
C)
mRNA synthesis done
clear
D)
tRNA synthesis done
clear
View Solution play_arrow
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question_answer104)
During translation initiation in prokaryotes, GTP is required for
A)
Formation of formyl-met-tRNA done
clear
B)
Binding of 30 S subunit of ribosome with mRNA done
clear
C)
Association of 30S mRNA with forrnyl met-tRNA done
clear
D)
Association of 50S subunit of ribosome with initiation complex done
clear
View Solution play_arrow
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question_answer105)
Match the components of lac operon of Escherichia coli and find out the correct combination
[a] | Structural gene | p. | Binding site for represser protein |
[b] | Operator gene | q. | Codes for represser protein |
[c] | Promoter gene | r. | Induces lactose transport from the medium |
[d] | Regulator gene | s. | Codes for enzyme proteins |
| | t. | Binding site for RNA polymerase |
A)
a-q, b-t, c-p, d-r done
clear
B)
a-r, b-s, c-t, d-p done
clear
C)
a-s, b-p, c-t, d-q done
clear
D)
a-t, b-s, c-q, d-p done
clear
View Solution play_arrow
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question_answer106)
Which of the following is the Pribnow box?
A)
5'TATAAT3' done
clear
B)
5' TAATTA3' done
clear
C)
5'AATAAT3' done
clear
D)
5'ATATTA3' done
clear
View Solution play_arrow
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question_answer107)
Which one of the following codons codes for the same information as UGC
A)
UGU done
clear
B)
UGA done
clear
C)
UAG done
clear
D)
AGG done
clear
View Solution play_arrow
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question_answer108)
Genetic code is degenerate because
A)
Codons have same energy level done
clear
B)
Each codon has a different meaning done
clear
C)
Each codon has many meanings done
clear
D)
Many codons have same meaning done
clear
View Solution play_arrow
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question_answer109)
Degeneration of a genetic code is attributed to
A)
Entire codon done
clear
B)
First member of a codon done
clear
C)
Second member of a codon done
clear
D)
Third member of a codon done
clear
View Solution play_arrow
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question_answer110)
During transcription, the DNA site at which RNA polymerase binds, is called
A)
Regulator done
clear
B)
Receptor done
clear
C)
Enhancer done
clear
D)
Promoter done
clear
View Solution play_arrow
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question_answer111)
During transcription, if nucleotide sequence of DNA strand, that is being coded is ATACG, then the nucleotide sequence in m-RNA would be
A)
UATGC done
clear
B)
TATGC done
clear
C)
TCTGG done
clear
D)
UAUGC done
clear
View Solution play_arrow
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question_answer112)
What is shown in the following figure? |
|
A)
Process of transcription in virus done
clear
B)
Process of transcription in bacteria done
clear
C)
Process of transcription in yeast done
clear
D)
Process of transcription in human done
clear
View Solution play_arrow
-
question_answer113)
Which one of the following triplet codes is correctly matched with its specificity for an amino acid in protein synthesis or as 'start' or 'stop' signal?
A)
UUU-Stop done
clear
B)
UGU-Leucine done
clear
C)
UAG-Tyrosine done
clear
D)
UCG-Start done
clear
View Solution play_arrow
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question_answer114)
A mutation of one base of the first codon, of a gene produces a non-functional protein such a mutation is called
A)
Non sense mutation done
clear
B)
Mis sense mutation done
clear
C)
Frameshift mutation done
clear
D)
Reverse mutation done
clear
View Solution play_arrow
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question_answer115)
Which of the following pairs is correctly matched with regard to the codon and the amino acid coded by it?
A)
UUU-valine done
clear
B)
A AA-lysine done
clear
C)
AUG cysteine done
clear
D)
CCC - Alanine done
clear
View Solution play_arrow
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question_answer116)
DNA fingerprinting is related to
A)
Molecular analysis of profiles of DNA samples done
clear
B)
Analysis of DNA samples using imprinting devices done
clear
C)
Techniques used for molecular analysis of different specimens of DNA done
clear
D)
Techniques used in identification of finger prints of different persons done
clear
View Solution play_arrow
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question_answer117)
Operon is
A)
Sequence of three nitrogen bases determining a single amino acid done
clear
B)
A set of closely placed genes regulating a metabolic pathway in prokaryotes done
clear
C)
Segment of DNA specifying a polypeptide done
clear
D)
Gene responsible for switching on and switching off of other genes done
clear
View Solution play_arrow
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question_answer118)
A coding sequence made of alternating C and U bases would form a polypeptide having
A)
Alternating leu or ser residues done
clear
B)
Either leu or ser residues done
clear
C)
Only ser residues done
clear
D)
Only leu residues done
clear
View Solution play_arrow
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question_answer119)
A gene of operon which forms the represser protein is :
A)
Operator done
clear
B)
Promoter done
clear
C)
Regulator done
clear
D)
Structural done
clear
View Solution play_arrow
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question_answer120)
Clover leaf secondary structure of t-RNA has a loop for:
A)
Three nucleotides of a codon done
clear
B)
Three nucleotides of an anticodon done
clear
C)
No nucleotides done
clear
D)
Both [a] and [b] done
clear
View Solution play_arrow
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question_answer121)
During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at the point. What is that sequence called?
A)
CAAT box done
clear
B)
GGTT box done
clear
C)
AAAT box done
clear
D)
TATA box done
clear
View Solution play_arrow
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question_answer122)
Protein synthesis in an animal cell occurs
A)
Only on the ribosomes present in cytosol done
clear
B)
On ribosomes present in cytoplasm as well as in mitochondria. done
clear
C)
Only on ribosomes attached to the nuclear envelope and endoplasmic reticulum done
clear
D)
On ribosomes present in the nucleolus as well as in cytoplasm. done
clear
View Solution play_arrow
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question_answer123)
Which one of the following makes use of RNA as a template to synthesize DNA?
A)
Reverse transcriptase done
clear
B)
DNA dependent RNA polymerase done
clear
C)
DNA polymerase done
clear
D)
RNA polymerase done
clear
View Solution play_arrow
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question_answer124)
In a given DNA segment ATG ACC AGG ACC CCA ACA, the first base gets mutated. The effect of this on coding by this DNA segment will result in :
A)
Complete change in the type as well as sequence of amino acids done
clear
B)
Change in first amino acid only done
clear
C)
No change in the sequence done
clear
D)
One amino acid less in protein done
clear
View Solution play_arrow
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question_answer125)
In the lac operon, the structural genes are switched off when
A)
Represser binds to operator done
clear
B)
Represser binds to promoter done
clear
C)
Represser binds to regulator done
clear
D)
Represser binds to inducer done
clear
View Solution play_arrow
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question_answer126)
Dr. Khorana and his colleagues synthesised an RNA molecule with repeating sequence of UG N-bases (UG UG UG UG UG UG). It produced a tetrapeptide with alternating sequence of cystein and valine. It proves that codons for cystein and valine are :
A)
UGU and GUU done
clear
B)
UGU and GUG done
clear
C)
UUG and GGU done
clear
D)
GUG and UGU done
clear
View Solution play_arrow
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question_answer127)
During protein synthesis AUG functions as the initiation codon in mRNA. What should be the anticodon in tRNA molecule that picks up and brings the amino acid specified by this codon?
A)
UAC done
clear
B)
TAC done
clear
C)
CAU done
clear
D)
GUA done
clear
View Solution play_arrow
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question_answer128)
DNA probes are copied from the messenger RNA molecules with the help of
A)
Restriction enzymes done
clear
B)
Reverse transcriptase done
clear
C)
DNA polymerase done
clear
D)
Adenosine deaminase done
clear
View Solution play_arrow
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question_answer129)
Consider the parts labelled in 1 and 2 respectively in the following diagram of the lac Operon and find out the correct sequences : |
|
A)
1 - Represser; 2 - Represser mRNA done
clear
B)
1 - Represser mRNA; 2 - Represser done
clear
C)
1 - Represser tRNA; 2 - Represser done
clear
D)
1 - Represser rRNA; 2 - Represser done
clear
View Solution play_arrow
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question_answer130)
Antiparallel strands of a DNA molecule mean that
A)
One strand turns anti-clockwise done
clear
B)
The phosphate groups of two DNA strands, at their ends, share the same position. done
clear
C)
The phosphate groups at the start of two DNA strands are in opposite position or pole done
clear
D)
One strand turns clockwise done
clear
View Solution play_arrow
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question_answer131)
Amino acid sequence, in protein synthesis is decided by the sequence of :
A)
tRNA done
clear
B)
mRNA done
clear
C)
cDNA done
clear
D)
rRNA done
clear
View Solution play_arrow
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question_answer132)
During protein synthesis in an organism, at one point the process comes to a halt. Select the group of the three codons from the following, from which any one of the three could bring about this halt :
A)
UUU, UCC, UAU done
clear
B)
UUC, UUA, UAC done
clear
C)
UAG, UGA, UAA done
clear
D)
UUG, UCA. UCG done
clear
View Solution play_arrow
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question_answer133)
Which is synthesized by RNA polymerase I:
A)
r-RNA sequence done
clear
B)
Prokaryotic m-RNA done
clear
C)
Eukaryotic m-RNA done
clear
D)
Prokaryotic r-RNA done
clear
View Solution play_arrow
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question_answer134)
The enzyme involved in transcription is :
A)
RNA polymerase done
clear
B)
DNA polymerase I done
clear
C)
DNA polymerase II done
clear
D)
DNA polymerase III done
clear
View Solution play_arrow
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question_answer135)
The Okazaki fragments in lagging DNA chain growth :
A)
Polymerize in the -3' to -5' direction and forms replication fork done
clear
B)
Prove semi-conservative nature of DNA replication done
clear
C)
Polymerize in -5 to -3' direction and explain -3' to -5 DNA replication done
clear
D)
Result in transcription done
clear
View Solution play_arrow
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question_answer136)
A sequential expression of a set of human genes occurs, when a steroid molecule binds to the :
A)
Messenger RNA done
clear
B)
DNA sequence done
clear
C)
Ribosome done
clear
D)
Transfer RNA done
clear
View Solution play_arrow
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question_answer137)
During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle like Structure. What is it's DNA binding sequence?
A)
AATT done
clear
B)
CACC done
clear
C)
TATA done
clear
D)
TTAA done
clear
View Solution play_arrow
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question_answer138)
Molecular basis of organ differentiation depends on the modulation in transcription by :
A)
Ribosome done
clear
B)
Transcription factors done
clear
C)
Anticodon done
clear
D)
RNA polymerase done
clear
View Solution play_arrow
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question_answer139)
In a mutational event, when adenine is replaced by guanine, it is the case of
A)
Frameshift mutation done
clear
B)
Transcription done
clear
C)
Transition done
clear
D)
Transversion done
clear
View Solution play_arrow
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question_answer140)
During transcription, the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in mRNA would be :
A)
TAT GC done
clear
B)
TCTGG done
clear
C)
UAUGC done
clear
D)
UA TGG done
clear
View Solution play_arrow
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question_answer141)
Which of the following statements is not true for retroviruses?
A)
DNA is not present at any stage in the life cycle of retroviruses done
clear
B)
Retroviruses carry genes for RNA dependent DNA polymerase done
clear
C)
The genetic material in mature retroviruses is RNA done
clear
D)
Retroviruses are causative agents for certain kinds of cancer in man. done
clear
View Solution play_arrow
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question_answer142)
Which form of RNA has a structure resembling clover leaf?
A)
rRNA done
clear
B)
hnRNA done
clear
C)
mRNA done
clear
D)
tRNA done
clear
View Solution play_arrow
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question_answer143)
Anticodon is present on :
A)
rRNA done
clear
B)
tRNA done
clear
C)
mtDNA done
clear
D)
mRNA done
clear
View Solution play_arrow
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question_answer144)
Regulator gene controls chemical synthesis (Operon concept) by :
A)
Inhibiting transcription of mRNA done
clear
B)
Inhibiting enzymes done
clear
C)
Inhibiting passage of mRNA done
clear
D)
Inhibiting substrate enzyme reaction done
clear
View Solution play_arrow
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question_answer145)
During translation initiation in prokaryotes, a GTP molecule is needed in :
A)
Association of 30S, mRNA with formyl-met-tRNA done
clear
B)
Association of 50S subunit of ribosome with initiation complex done
clear
C)
Formation of formyl-met-tRNA done
clear
D)
Binding of 30 subunits of ribosome with mRNA done
clear
View Solution play_arrow
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question_answer146)
What would happen if in a gene encoding a polypeptide of 50 amino acids will be (UAC) is mutated of UAA?
A)
A polypeptide of 49 amino acids will be formed done
clear
B)
A polypeptide of 25 amino acids will be formed done
clear
C)
A polypeptide of 24 amino acids will be formed done
clear
D)
Two polypeptides of 24 and 25 amino acids will be formed done
clear
View Solution play_arrow
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question_answer147)
Non-genetic sex determination is found in:
A)
Fruitfly done
clear
B)
Bonellia done
clear
C)
Cow done
clear
D)
Birds done
clear
View Solution play_arrow
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question_answer148)
According to wobble hypothesis
A)
The process of polypeptide chain elongation has been established done
clear
B)
First base is unstable done
clear
C)
Second base is most unstable done
clear
D)
Third base is most unstable done
clear
View Solution play_arrow
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question_answer149)
In bacterial DNA replication, synthesis starting from the site of origin of replication
A)
Involves RNA primers done
clear
B)
Requires telomerase done
clear
C)
Proceeds unidirectionally done
clear
D)
Moves bidirectionally done
clear
View Solution play_arrow
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question_answer150)
In the DNA molecule:
A)
Proportion of adenine in relation to thymine varies with organism done
clear
B)
There are two strands which run antiparallel - one in 5'-3' direction and other in 3'-5' direction done
clear
C)
The total amount of purine nucleotides and pyrimidine nucleotides is not always equal done
clear
D)
There are two strands which run parallel in the 5'-3' direction done
clear
View Solution play_arrow
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question_answer151)
Which one of the following pairs of nitrogenous bases of nucleic acids is wrongly matched with category mentioned against it?
A)
Guanine, adenine - purines done
clear
B)
Adenine, thymine - purines done
clear
C)
Thymine, uracil - pyrimidines done
clear
D)
Uracil, cytosine - pyrimidines done
clear
View Solution play_arrow
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question_answer152)
What is antisense technology?
A)
When a piece of RNA that is complimentary in sequence is used to stop expression of specific gene done
clear
B)
RNA polymerase producing DNA done
clear
C)
A cell displaying a foreign antigen used for synthesis of antigens done
clear
D)
Production of somaclonal variants in tissue culture. done
clear
View Solution play_arrow
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question_answer153)
Which one of the following is having ssRNA?
A)
TMV done
clear
B)
\[{{T}_{2}}\]bacteriophage done
clear
C)
Pox virus done
clear
D)
\[\phi \times 174\] done
clear
View Solution play_arrow
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question_answer154)
Length of DNA in human is about?
A)
1.2 m done
clear
B)
2.2 m done
clear
C)
3.2 m done
clear
D)
4.2 m done
clear
View Solution play_arrow
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question_answer155)
The portion of DNA which contains information for an entire polypeptide is called :
A)
Cistron done
clear
B)
Muton done
clear
C)
Recon done
clear
D)
Operon done
clear
View Solution play_arrow
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question_answer156)
DNA element with ability to change its position, is called :
A)
Cistron done
clear
B)
Transposon done
clear
C)
Intron done
clear
D)
Recon done
clear
View Solution play_arrow
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question_answer157)
Which one of the following pairs is correctly matched with regard to the codon and the amino acid coded by it?
A)
UUA-valine done
clear
B)
AAA-lysine done
clear
C)
AUG-cysteine done
clear
D)
CCC-alanine done
clear
View Solution play_arrow
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question_answer158)
Out of 64 codons only 61 codes for the 20 different amino acids. This character of genetic code is called :
A)
Degeneracy done
clear
B)
Non ambiguous nature done
clear
C)
Redundancy done
clear
D)
Overlapping done
clear
View Solution play_arrow
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question_answer159)
mRNA direct the building of proteins through a sequence of :
A)
Exons done
clear
B)
Introns done
clear
C)
Codons done
clear
D)
Anticodons done
clear
View Solution play_arrow
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question_answer160)
Beadle and Tatum showed that each kind of mutant bread mould they studied lacked a specific enzyme. Their experiments demonstrated that :
A)
Cells need specific enzymes in order to function done
clear
B)
Genes are made up of DNA done
clear
C)
Enzymes are required to repair damage done
clear
D)
Genes carry information for making proteins done
clear
View Solution play_arrow
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question_answer161)
There is no DNA in
A)
A mature spermatozoan done
clear
B)
Hair root done
clear
C)
An enucleated ovum done
clear
D)
Mature RBC done
clear
View Solution play_arrow
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question_answer162)
Semi-conservative replication of DNA was first time demonstrated in :
A)
Drosophila melanogaster done
clear
B)
Escherichia toll done
clear
C)
Streptococcus pneumonia done
clear
D)
Salmonella typhimurium done
clear
View Solution play_arrow
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question_answer163)
What is not true for genetic code?
A)
It is degenerate done
clear
B)
It is ambiguous done
clear
C)
A codon in mRNA is read in a contiguous fashion done
clear
D)
It is nearly universal done
clear
View Solution play_arrow
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question_answer164)
Formation of both peptide and glycosidic bonds involves :
A)
Hydration done
clear
B)
Dehydration done
clear
C)
Esterification done
clear
D)
Acidification done
clear
View Solution play_arrow
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question_answer165)
What will be the correct gene expression pathway?
A)
Gene-mRNA-transcription-translation-protein done
clear
B)
Transcription-gene-translation-mRNA-protein done
clear
C)
Gene-transcription-mRNA-translation-protein done
clear
D)
Gene-translation-mRNA-transcription-protein done
clear
View Solution play_arrow
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question_answer166)
The main aim of the human genome project is
A)
To introduce new genes into humans done
clear
B)
To identify and sequence all the genes present in human DNA done
clear
C)
To develop better techniques for comparing two different human DNA samples done
clear
D)
To remove disease causing genes from human DNA. done
clear
View Solution play_arrow
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question_answer167)
In genetic fingerprinting, the 'probe' refers to
A)
A radioactively labelled single stranded DNA molecule done
clear
B)
A radioactively labelled single stranded RNA molecule done
clear
C)
A radioactively labelled double stranded RNA molecule done
clear
D)
A radioactively labelled double stranded DNA molecule. done
clear
View Solution play_arrow
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question_answer168)
Match the codons with their respective amino acids and choose the correct answer :
| Column - I | | Column - II |
[A] | UUU | 1. | Serine |
[B] | GGG | 2. | Methionine |
[C] | UCU | 3. | Phenylalanine |
[D] | CCC | 4. | Glycine |
[E] | AUG | 5. | Proline |
A)
A - 3, B - 4, C - 1, D - 5, E - 2 done
clear
B)
A - 3, B - 1, C - 4, D - 5, E - 2 done
clear
C)
A - 3, B - 4, C - 5, D - 1, E - 2 done
clear
D)
A - 2, B - 4, C - 1, D - 5, E - 3 done
clear
View Solution play_arrow
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question_answer169)
In the Lac operon system, (\[\beta \]-galactosidase is coded by :
A)
a-gene done
clear
B)
i-gene done
clear
C)
1-gene done
clear
D)
z-gene done
clear
View Solution play_arrow
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question_answer170)
Consider the following statements |
I. r-RNA provides the template for synthesis of proteins |
II. t-RNA brings amino acids and reads the genetic code |
III. RNA polymerase binds to promoter and initiates transcription |
IV. A segment of DNA coding for polypeptide is called intron |
A)
I and III are correct done
clear
B)
I and II are correct done
clear
C)
I, II and III are correct done
clear
D)
II and III are correct done
clear
View Solution play_arrow
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question_answer171)
Locations on sites in the human DNA where single base DNA differences occurs are called :
A)
Repetitive DNA done
clear
B)
VNTR done
clear
C)
Snips done
clear
D)
SSBP done
clear
View Solution play_arrow
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question_answer172)
The one aspect which is not a salient feature of genetic code, is its being
A)
Specific done
clear
B)
Degenerate done
clear
C)
Ambiguous done
clear
D)
Universal done
clear
View Solution play_arrow
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question_answer173)
Which one of the following does not follow the central dogma of molecular biology ?
A)
HIV done
clear
B)
Pea done
clear
C)
Mucor done
clear
D)
Chlamydomonas done
clear
View Solution play_arrow
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question_answer174)
In eukaryotes cell transcription, RNA splicing and RNA capping take place inside the
A)
ribosomes done
clear
B)
nucleus done
clear
C)
dictyosomes done
clear
D)
ER done
clear
View Solution play_arrow
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question_answer175)
Select the two correct statements out of the four (1-4), given below about lac operon : |
1. Glucose or galactose may bind with the represser and inactivate it |
2. In the absence of lactose the represser binds with the operator region |
3. The z-gene codes for permease |
4. This was elucidated by Francois Jacob and Jacque Monod |
The correct statements are |
A)
1 and 4 done
clear
B)
2 and 3 done
clear
C)
1 and 3 done
clear
D)
2 and 4 done
clear
View Solution play_arrow
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question_answer176)
The lac operon consists of
A)
four regulatory genes only done
clear
B)
one regulatory gene and three structural genes done
clear
C)
two regulatory genes and two structural genes done
clear
D)
three regulatory genes and three structural genes done
clear
View Solution play_arrow
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question_answer177)
The 3' - 5' phosphodiester linkages inside a polynucleotide chain serve to join :
A)
One DNA strand with the other DNA strand done
clear
B)
One nucleoside with another nucleoside done
clear
C)
One nucleotide with another nucleotide done
clear
D)
One nitrogenous base with pentose sugar done
clear
View Solution play_arrow
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question_answer178)
In transcription in eukaryotes, heterogeneous nuclear RNA (hnRNA) is transcribed by :
A)
RNA polymerase I done
clear
B)
RNA polymerase II done
clear
C)
RNA polymerase III done
clear
D)
All of these done
clear
View Solution play_arrow
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question_answer179)
Non-proteinaceous enzyme that acts as a catalyst for the formation of peptide bond is :
A)
Spliceosome done
clear
B)
Ribozyme done
clear
C)
RNA polymerase I done
clear
D)
RNA polymerase III done
clear
View Solution play_arrow
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question_answer180)
Methyl guanosine triphosphate is added to the 5' end of hnRNA in a process of :
A)
Splicing done
clear
B)
Capping done
clear
C)
Tailing done
clear
D)
None of these done
clear
View Solution play_arrow
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question_answer181)
UTR is the part of
A)
rRNA done
clear
B)
tRNA done
clear
C)
mRNA done
clear
D)
scRNA done
clear
View Solution play_arrow
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question_answer182)
RNA polymerase II is responsible for transcription of :
A)
rRNA done
clear
B)
hnRNA done
clear
C)
tRNA done
clear
D)
snRNA done
clear
View Solution play_arrow
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question_answer183)
Which of the following sequences will be produced as a result of transcription of the DNA sequence CGATTACAG?
A)
GCUAAUGUC done
clear
B)
CGUAAUCUG done
clear
C)
GCTAATGTC done
clear
D)
GCUAATCTG done
clear
View Solution play_arrow
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question_answer184)
Har Govind Khorana is known for :
A)
Discovery of DNA structure done
clear
B)
Synthesis of protein done
clear
C)
Discovery of DNA ligase enzyme done
clear
D)
Discovery of tRNA done
clear
View Solution play_arrow
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question_answer185)
The lac operon consists of :
A)
Four regulatory genes only done
clear
B)
One regulatory gene and three structural genes done
clear
C)
Two regulatory genes and two structural genes done
clear
D)
Three regulatory genes and three structural genes done
clear
View Solution play_arrow
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question_answer186)
The Lac operon "Inducer Lactose" serves as an enzyme substrate for
A)
Transacetylase done
clear
B)
Endonuclease done
clear
C)
Permease done
clear
D)
Beta-galactosidase done
clear
View Solution play_arrow
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question_answer187)
DNA finger printing has application in the field of
A)
Forensic Science done
clear
B)
Genetic Biodiversity done
clear
C)
Evolutionary Biology done
clear
D)
All the above done
clear
View Solution play_arrow
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question_answer188)
Given below is a sample of a portion of DNA strand giving the base sequence on the opposite strands. What is so special shown in it? |
5' - GAATTC - 3' |
3' - CTTAAG - 5' |
A)
Deletion mutation done
clear
B)
Start codon at the 5' end done
clear
C)
Palindromic sequence of base pair done
clear
D)
Replication completed done
clear
View Solution play_arrow
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question_answer189)
What are those structure that appear as "beads-on-string" in the chromosomes when viewed under electron microscope ?
A)
Nucleotides done
clear
B)
Nucleosomes done
clear
C)
Base pairs done
clear
D)
Genes done
clear
View Solution play_arrow
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question_answer190)
In genetic code, 61 codons code for 20 different types of amino acids. This is called :
A)
Colinearity done
clear
B)
Commaless done
clear
C)
Degeneracy done
clear
D)
Nonambiguity done
clear
View Solution play_arrow
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question_answer191)
The term, genetic RNA refers to :
A)
genetic material of RNA viruses done
clear
B)
RNA that carries genetic message done
clear
C)
RNA that helps gene regulation in lac-operon done
clear
D)
RNA present in mitochondria done
clear
View Solution play_arrow
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question_answer192)
What will be the codon in mRNA if the DNA codes are ATG-CAG ?
A)
TAC - GTC done
clear
B)
UAC - GUC done
clear
C)
UCA - TUA done
clear
D)
TCA - GTC done
clear
View Solution play_arrow
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question_answer193)
Removal of RNA polymerase III from nucleoplasm will affected the synthesis of
A)
mRNA done
clear
B)
rRNA done
clear
C)
tRNA done
clear
D)
hn RNA done
clear
View Solution play_arrow
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question_answer194)
Which one of the following is not a part of a transcription unit in DNA?
A)
A promoter done
clear
B)
The structural gene done
clear
C)
The inducer done
clear
D)
A terminator done
clear
View Solution play_arrow
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question_answer195)
If one or DNA has the nitrogenous base sequence as ATCTG, what would be the complementary RNA strand sequence ?
A)
AACTG done
clear
B)
ATCGU done
clear
C)
TTAGU done
clear
D)
UAGAC done
clear
View Solution play_arrow
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question_answer196)
Which one of the following represents a palindromic sequence in DNA ?
A)
B)
C)
D)
View Solution play_arrow
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question_answer197)
Read the following four statements (a - d) |
[a] In transcription, adenosine pairs with uracil |
[b] Regulation of lac operon by represser is referred to as positive regulation |
[c] The human genome has approximately 50,000 genes |
[d] Hemophilia is a sex-linked recessive disease |
How many of the above statements are right? |
A)
Four done
clear
B)
One done
clear
C)
Two done
clear
D)
Thee done
clear
View Solution play_arrow
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question_answer198)
Which one of the following is a wrong statement regarding mutations?
A)
UV and Gamma rays are mutagens done
clear
B)
Change in a single base pair of DNA does not cause mutation done
clear
C)
Deletion and insertion of base pairs cause frame shift mutations done
clear
D)
Cancer cells commonly show chromosomal aberrations done
clear
View Solution play_arrow
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question_answer199)
Choose the correct statement pertaining to genetic code
A)
It includes 61 codons for amino acids and 3 stop codons done
clear
B)
Is universal, and has 3 bases per codon done
clear
C)
Some amino acids are coded by multiple codons done
clear
D)
All of these done
clear
View Solution play_arrow
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question_answer200)
Identify the correct sequence of events in the viral replication process. |
(I) Eclipse |
(II) Maturation |
(III) Adsorption |
(IV) Assembly |
(V) Penetration |
(VI) Lysis |
A)
\[I\to II\to III\to IV\to V\to VI\] done
clear
B)
\[II\to I\to III\to IV\to V\to VI\] done
clear
C)
\[III\to V\to I\to II\to IV\to VI\] done
clear
D)
\[III\to V\to I\to IV\to II\to VI\] done
clear
View Solution play_arrow
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question_answer201)
Select the correct statement regarding protein synthesis
A)
When the small subunit of the ribosome encounters an mRNA the process of translation begins done
clear
B)
Peptidase catalyses the formation of peptide bond done
clear
C)
UTRs are present between the start codon and stop codon done
clear
D)
At the end of translation, the release factor binds to the initiation codon done
clear
View Solution play_arrow
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question_answer202)
To which of the following factors, RNA polymerase binds transiently to initiate transcription?
A)
rho done
clear
B)
beta done
clear
C)
gamma done
clear
D)
sigma done
clear
View Solution play_arrow
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question_answer203)
The enzyme(s) responsible for the transcription of snRNAs in eukaryotes is/are
A)
RNA polymerase I done
clear
B)
RNA polymerase I and II done
clear
C)
RNA polymerase II done
clear
D)
RNA polymerase III done
clear
View Solution play_arrow
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question_answer204)
Consider the parts labelled in 1, 2, 3 and 4 respectively in the following diagram of the lac Operon and find out the correct sequences : |
|
A)
1 - Translation; 2 - \[\beta \] - galactosidase; 3 - Permease; 4 - Transacetylase done
clear
B)
1 - Replication; 2 galactosidase; 3 - Permease; 4 - Transacetylase done
clear
C)
1 - Transcription; 2 galactosidase; 3 - Permease; 4 - Endonuclease done
clear
D)
1 - Transcription; 2 galactosidase; 3 - Permease; 4 - Transacetylase done
clear
View Solution play_arrow
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question_answer205)
Choose the wrong statement from the following
A)
VNTR belong to a class of micro satellite DNA done
clear
B)
DNA sequencers work on the principle developed by Frederick Sanger done
clear
C)
HGP was coordinated by US Department of Energy and the National Institute of Health done
clear
D)
DNA finger printing involves identifying similarities in repetitive DNA done
clear
View Solution play_arrow
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question_answer206)
In lac operon, the genes a, i, y and z code respectively for
A)
represser protein, permease, \[\beta \]-galactosidase, transacetylase done
clear
B)
transacetylase, permease, \[\beta \]-galactosidase, represser protein done
clear
C)
permease, transacetylase, represser protein, \[\beta \]-galactosidase done
clear
D)
transacetylase, represser protein, permease, \[\beta \]-galactosidase done
clear
View Solution play_arrow
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question_answer207)
Addition or deletion of a single nucleotide results in which type of mutation?
A)
Deficiency done
clear
B)
Duplication done
clear
C)
Frameshift mutation done
clear
D)
none of these done
clear
View Solution play_arrow
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question_answer208)
Which of the following corresponds to mutagens ?
A)
Chemical and radiations which cause changes in the genetic material of a cell done
clear
B)
Various archaebacteria that produce methane done
clear
C)
Chemical which reacts with ozone molecules and destroy them done
clear
D)
RNA molecules that infect plant cells and cause diseases done
clear
View Solution play_arrow
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question_answer209)
Which enzymes will be produced in a cell in which there is a nonsense mutation in the lac Y gene ?
A)
Transacetylase done
clear
B)
Lactose permease and transacetylase done
clear
C)
P-galactosidase done
clear
D)
Lactose permease done
clear
View Solution play_arrow
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question_answer210)
The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C. \[DNA\xrightarrow{A}mRNA\xrightarrow{B}protein\xrightarrow[C]{\Pr oposed\,by}\]s
A)
A - transcription B -translation C - Francis Crick done
clear
B)
A - translation B - extension C - Rosalind Franklin done
clear
C)
A - transcription B - replication C - James Watson done
clear
D)
A - translation B - transcription C - Erevin Chargaff done
clear
View Solution play_arrow
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question_answer211)
One of the most frequently used techniques in DNA fingerprinting is
A)
VNTR done
clear
B)
SSCP done
clear
C)
SCAR done
clear
D)
AFLP done
clear
View Solution play_arrow
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question_answer212)
In an inducible operon, the genes are
A)
usually not expressed unless a signal turns them "on". done
clear
B)
usually expressed unless a signal turns them "off". done
clear
C)
never expressed done
clear
D)
always expressed done
clear
View Solution play_arrow
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question_answer213)
Satellite RNAs are present in some
A)
viroids done
clear
B)
prions done
clear
C)
bacteriophages done
clear
D)
plant viruses. done
clear
View Solution play_arrow
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question_answer214)
The most unstable RNA is
A)
messenger RNA done
clear
B)
soluble RNA done
clear
C)
ribosomal RNA done
clear
D)
heterogeneous nuclear RNA done
clear
View Solution play_arrow
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question_answer215)
The portion of a eukaryotic gene which is transcribed but not translated is
A)
exon done
clear
B)
intron done
clear
C)
cistron done
clear
D)
codon done
clear
View Solution play_arrow
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question_answer216)
Read the statements A and B and select the correct option. |
Statement A: Synthesis of mRNA takes place in 5' - 3' direction. |
Statement B: Reading of mRNA is always in 3' - 5' direction. |
A)
Both the statements are wrong done
clear
B)
Statement A is wrong, B is correct. done
clear
C)
Statement B is wrong, A is correct. done
clear
D)
Both the statements A and B are correct. done
clear
View Solution play_arrow
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question_answer217)
Match the entries in Column - I with those of Column - II and choose the correct answer.
| Column - I | | Column - II |
[a] | Restriction endonucleses | (p) | Kohler and Milstein |
[b] | Polymerase chain reaction | (q) | Alee Jeffreys |
[c] | DNA fingerprinting | (r) | Arber |
[d] | Monoclonal antibodies | (s) | Karry Mullis |
A)
p, q, r, s done
clear
B)
q, r, s, p done
clear
C)
r, s, q, p done
clear
D)
r, s, p, q done
clear
View Solution play_arrow
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question_answer218)
In one of the techniques of recombinant insulin production the genes for a and P polypeptides were inserted into the plasmid by the side of
A)
antibiotic resistance gene done
clear
B)
lac z promoter gene done
clear
C)
\[\beta \]-galactosidase gene done
clear
D)
ori site done
clear
View Solution play_arrow
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question_answer219)
Genes that are involved in turning on or off the transcription of a set of structural genes are called
A)
polymorphic genes done
clear
B)
operator genes done
clear
C)
represser genes done
clear
D)
regulatory genes done
clear
View Solution play_arrow
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question_answer220)
Which of the following takes place in DNA fingerprinting?
A)
A positive identification can be made done
clear
B)
Multiple restriction enzyme digests generate unique fragments done
clear
C)
The polymerase chain reaction amplifies between fewer DNA done
clear
D)
The variability of repeated sequences between two restriction sites is evaluated done
clear
View Solution play_arrow
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question_answer221)
Which one of the following is wrongly matched?
A)
Represser protein - Binds to operator to stop enzyme synthesis. done
clear
B)
Operon - Structural genes, operator and promoter. done
clear
C)
Transcription - Writing information from DNA to t-RNA. done
clear
D)
Translation - Using information in ot-rna to make protein. done
clear
View Solution play_arrow
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question_answer222)
Select the correct option from the followings :
A)
B)
C)
D)
View Solution play_arrow
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question_answer223)
Commonly used vectors for human genome sequencing are
A)
Expression Vectors done
clear
B)
T/A Cloning Vectors done
clear
C)
T-DNA done
clear
D)
BAC and YAC done
clear
View Solution play_arrow
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question_answer224)
Read the following statements and choose the correct option. |
I. RNA polymerase associates transiently with 'Rho' factor to initiate transcription. |
II. In bacteria, transcription and translation takes place in the same compartment. |
II. RNA polymerase I is responsible for transcription of tRNA |
III. When hnRNA undergoes capping process, adenylate residues are added at 3' end in a template independent manner |
V. hnRNA is the precursor of mRNA |
A)
II only is correct done
clear
B)
II, III and V only are correct done
clear
C)
III and IV only are correct done
clear
D)
II and V only are correct done
clear
View Solution play_arrow
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question_answer225)
Choose the correct statement of the following :
A)
Haploid content of human DNA is \[4.6\times {{10}^{6}}\,\,bp\]. done
clear
B)
A nitrogenous base is linked to pentose sugar through phosphodiester linkage done
clear
C)
X-ray diffraction data of Maurice Wilkins and Rosalind Franklin was the basis of Watson and Crick's DNA model done
clear
D)
DNA is an acidic substance was first identified by Watson and Crick done
clear
View Solution play_arrow
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question_answer226)
Aminoacylation of tRNA is essential for
A)
Replication of RNA done
clear
B)
Formation of peptide bond done
clear
C)
splicing done
clear
D)
Initiation of transcription done
clear
View Solution play_arrow
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question_answer227)
Which site of the tRNA pairs through hydrogen bonding with the triplet codes on mRNA?
A)
Codon done
clear
B)
5' end of tRNA done
clear
C)
3' end of tRNA done
clear
D)
Anticodon done
clear
View Solution play_arrow
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question_answer228)
Find the wrongly matched pair :
A)
Har Gobind Khorana - synthesized RNA molecules chemically done
clear
B)
George Gamow - codon is triplet done
clear
C)
Meselson and Stahl - regulation of gene expression done
clear
D)
Alee Jeffreys - DNA finger printing done
clear
View Solution play_arrow
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question_answer229)
If an inheritable mutation is observed in a population at high frequency, it is referred as
A)
DNA polymorphism done
clear
B)
expressed sequence tag done
clear
C)
sequence annotation done
clear
D)
linkage done
clear
View Solution play_arrow
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question_answer230)
An eukaryote, RNA polymerase II transcribes
A)
hnRNA done
clear
B)
18S rRNA done
clear
C)
28S rNA done
clear
D)
tRNA done
clear
View Solution play_arrow
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question_answer231)
Which of the following events would occur in 'Lac operon' of E. coli when the growth medium has high concentration of lactose?
A)
The represser protein attaches to the promoter sequence and derepresses the operator done
clear
B)
The structural genes fail to produce polycistronic mRNA done
clear
C)
The inducer molecule binds to represser protein and RNA polymerase binds to promoter sequence done
clear
D)
The represser protein binds to RNA polymerase and prevents translation done
clear
View Solution play_arrow
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question_answer232)
Statement A: The primary transcript produced in eukaryotes is translated without undergoing any modification or processing. |
Statement B: The hnRNA in humans has exons and introns. |
A)
Statement B is correct and statement A is wrong done
clear
B)
Both the statements A and B are correct done
clear
C)
Statement A is correct and statement B is wrong done
clear
D)
Both the statements A and B are wrong done
clear
View Solution play_arrow
-
question_answer233)
Some of the steps of DNA fingerprinting are given below. Identify the correct sequence from the options given. |
I. Electrophoresis of DNA fragments |
II. Hybridisation with DNA probe |
III. Digestion of DNA by RENs |
IV. UT radiography |
V. Blotting of DNA fragments to nitrocellulose membrane |
A)
III - I - II - V - IV done
clear
B)
III - I - V - II - IV done
clear
C)
I - V - III - II - IV done
clear
D)
I - III - V - IV - II done
clear
View Solution play_arrow
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question_answer234)
During the transcription, if nucleotide sequence of DNA strand being coded is ATACG, then the nucleotide sequence of mRNA would be
A)
UATGC done
clear
B)
TATGC done
clear
C)
UAUGC done
clear
D)
TATGG done
clear
View Solution play_arrow
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question_answer235)
The sequence of nucleotides AUGCUUCUC indicates that it is a segment of
A)
sense strand of DNA done
clear
B)
anti sense strand of DNA done
clear
C)
RNA strand done
clear
D)
polypeptide chain done
clear
View Solution play_arrow
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question_answer236)
In DNA fingerprinting technique, probe is used for hybridization of DNA fragments.
A)
double stranded RNA done
clear
B)
double stranded non-radioactive DNA done
clear
C)
single stranded radioactive DNA done
clear
D)
single stranded radioactive RNA done
clear
View Solution play_arrow
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question_answer237)
Of the total number of genes estimated in human genome, nearly 10 percent are contained in
A)
chromosome 11 done
clear
B)
chromosome 21 done
clear
C)
Y chromosome done
clear
D)
chromosome 1 done
clear
View Solution play_arrow
-
question_answer238)
The technique of DNA finger printing relies on
A)
repetitive DNA done
clear
B)
mini satellite DNA done
clear
C)
Both [a] and [b] done
clear
D)
None of these done
clear
View Solution play_arrow
-
question_answer239)
In DNA finger printing, the process of DNA hybridization with the help of specific DNA probe is described as
A)
western blotting done
clear
B)
northern blotting done
clear
C)
southern blotting done
clear
D)
all the above done
clear
View Solution play_arrow
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question_answer240)
Heterogeneous nuclear RNA (hnRNA) is converted to mRNA by
A)
splicing done
clear
B)
capping done
clear
C)
tailing done
clear
D)
all the above done
clear
View Solution play_arrow
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question_answer241)
DNA polymerase that helps in DNA replication is of
A)
Two types done
clear
B)
Three types done
clear
C)
Four types done
clear
D)
Only one type done
clear
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question_answer242)
In bacterial DNA replication, synthesis starting from the site of origin of replication
A)
Involves RNA primers done
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B)
Requires telomerase done
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C)
Proceeds unidirectionally done
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D)
Move bidirectionally done
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question_answer243)
Which one is mostly transcribed?
A)
Single copy of DNA sequence done
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B)
Highly repetitive DNA sequence done
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C)
Middle repetitive DNA sequence done
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D)
Only RNA sequence done
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question_answer244)
During replication of a bacterial chromosome, DNA synthesis starts from a replication, origin site and :
A)
RNA primers are involved done
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B)
In facilitated by telomerase done
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C)
Moves in one direction of the site done
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D)
Moves in bi-directional way done
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question_answer245)
During polynucleotide synthesis by the following enzymes, in which case elongation occurs in \[5'\to 3'\]direction ?
A)
DNA polymerase done
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B)
RNA polymerase done
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C)
Reverse transcriptase done
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D)
All the above done
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