question_answer 64)

  Can Gatterman-Koch reaction be considered similar to Friedel Craft's acylation ? Discuss.

Answer:

                  Yes. Gattermann-Koch reaction can be considered similar to Friedel-Crafts acylation. The reason being that in p.C. acylation reactions, benzene (or any other arene) is treated with an acid chloride in presence of anhyd. . Since  (formyl chloride) is not stable, therefore, in Gattermann-Koch reaction, it is prepared in situ by reacting CO with HCl gas in presence of anhydrous . Thus, Gattermann-Koch "action is similar to F.C. acylation reaction.