Answer:
(d) Sickle-cell anaemia is an
autosome linked recessive trait. In this genetic disorder point mutation in
p-globin chain results in change of glutamate (glutamic acid) to valine at sixth
position. Only the homozygous individuals for,i.e., show the
diseased phenotype. The heterozygous individuals
are carriers.
It is also known that heterozygotes,
having both types of haemoglobin, show resistance to malaria infection because
the body targets the P. falciparum (protozoan) infected cells for destruction
of RBC.
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