Answer:
A sigmoid curve is obtained when
percentage saturation of haemoglobin with O2 is plotted against the
pO2. This curve is called the oxygen dissociation curve and is
highly useful in studying the effect of factors like pCO2, H+
concentration, etc., on binding of O2 with haemoglobin.
In the alveoli, where there is high pO2, low pCO2,
lesser H+ concentration and lower temperature, the factors are all
favourable for the formation of oxyhaemoglobin, whereas in the tissues, where
low pO2, high pCO2, high H+ concentration and
higher temperature exist, the conditions are favourable for dissociation of
oxygen from the oxyhaemoglobin. This clearly indicates that O2 gets
bound to haemoglobin in the lung surface and gets dissociated at the tissues.
Every 100 mL of oxygenated blood can deliver around 5 mL of O2 to the tissues
under normal physiological conditions.
You need to login to perform this action.
You will be redirected in
3 sec
