A) Substrate binds with enzyme as its active site
B) Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate
C) A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate
D) Malonate is a competitive inhibitor of succinic dehydrogenase
Correct Answer: B
Solution :
Inhibition of succinic dehydrogenase by malonate is an example of competitive inhibition. Competitive inhibition occurs when enzyme and inhibitor both have more or less similar structure are present in higher Concentration. Thus, both enzyme and inhibitor for competer for the active site of enzyme resulting to the decrease in the enzymatic actively.
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