Manipal Medical Manipal Medical Solved Paper-2012

  • question_answer
    In which of the following there is no defect in. the sex chromosome?

    A)  Turners syndrome

    B)  Downs syndrome

    C)  Colour blindness

    D)  Klinefelters syndrome

    Correct Answer: B

    Solution :

     Downs syndrome (mongolian idiocy) is a congenital disorder caused by trisomy of chromosome 21, often by non-disjunction. It is characterised by mental retardation, simian palm, as mongoloid facial features. Turners syndrome is due to monosomy of sex chromosome, i.e., XO. It was described by Turner 1938. Colour blindness is a recessive sex linked (X) trait in which affected individual can not distinguish red colour from green colour. Klinefelters syndrome is due to an extra X-chromosome to man (male), i.e., trisomy of sex chromosome.


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