Manipal Medical Manipal Medical Solved Paper-2007

  • question_answer
    The telomeres of eukaryotic chromosomes consists of short sequences of

    A)  thymine rich repeats

    B)  cytosine rich repeats

    C)  adenine rich repeats

    D)  guanine rich repeats

    Correct Answer: D

    Solution :

    Telomeres have been shown to have unique structures that include short nucleotide sequences present as tandemlyrepeated units. The basic repeat sequence in all the species studied has the pattern\[5-{{T}_{1-4}}{{A}_{0-1}}{{G}_{1-8}}-3\].Same repeated sequence is found in at the end of all chromosomes in a species. Not only this, same telomere sequence may occur in widely divergent species (eg, Human beings, Neurospom and some acellular slime molds). Clusters of G residues in one strand and C residues in the other characterise telomeric DNA. Also, in some species the telomeres terminate with a single-stranded DNA (12-16 nucleotides long) rich in guanine.


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