JCECE Medical JCECE Medical Solved Paper-2007

  • question_answer
    Enzymes found attached to inner membrane of mitochondria instead of matrix is/are

    A)  succinic dehydrogenase

    B)  cytochrome oxidase

    C)  both [a] and [b]

    D)  malic dehydrogenase

    Correct Answer: C

    Solution :

     All the enzymes of Krebs cycle, fatty acid synthesis and amino acid synthesis are found in matrix but succinic dehydrogenase and cytochrome oxidase are present on inner membrane of mitochondria. The mitochondrial inner membrane contains enzymes of electron transport pathway ie, NAD, FAD, diphospho pyredine     nucleotide     dehydrogenase, ubiquenone or coenzyone\[{{\text{Q}}_{10}},\] copper and iron; ATP synthase, succinate dehydrogenase\[\text{ }\!\!\beta\!\!\text{ }-\]hydroxybutyrate dehydrogenase etc. Mitochondrial   matrix   contains   malate dehydrogenase-isocitrate     dehydrogenase, fumarase, aconitase, citrate synthase, \[\text{ }\!\!\alpha\!\!\text{ }-\]keto acid dehydrogenase, \[\text{ }\!\!\beta\!\!\text{ }-\]oxidation enzymes, etc.


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