A) prophase stage
B) anaphase stage
C) telophase stage
D) metaphase stage
Correct Answer: D
Solution :
?Colchicine?, a pale yellow crystalline alkaloid, extracted from the conns of Autumn crocus (Colchicum autumnale), interfers in mitosis during spindle microtuble formation. It does so by breaking microtubules. Mitotic arrest is seen with the treatment of colchicine in plant and animal cells. Infact, the cell treated with colchicine, completes prophase but since, spindle fibres are not formed so, stage next to prophase i.e., metaphase is arrested. It leads to duplication of chromosome, resulting in autopolyploidy.
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