Chhattisgarh PMT Chhattisgarh PMT Solved Paper-2004

  • question_answer
    The drug streptomycin inhibits the process of

    A)  prokaryotic translation

    B)  eukaryotic translation

    C)  prokaryotic transcription

    D)  eukaryotic transcription

    Correct Answer: A

    Solution :

    Streptomycin acts by inhibiting protein synthesis in bacteria via altering the structure of 30S subunit. This alteration results to mis-reading of mRNA code. The drug is a rapid bactericidal and more potent against extra cellular bacteria than intracellular one because of the fact that Mg2+ and \[{{\text{H}}_{\text{3}}}\text{PO}\,_{\text{4}}^{\text{2-}}\](ions present inside cell) decrease the streptomycin activity.


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