A) Chromosomal aberration
B) Somatic mutation
C) X-linked mutation
D) All of the above
Correct Answer: C
Solution :
Haemophilia is a X-linked mutation or sex linked inheritance. In this disease, blood fails to clot when exposed to air. It is also called bleeder's disease and it was first studied by John Cotto in 1803. The most famous pedigree of haemophilia was discovered by Haldane in the royal families of Europe. In this disease, patient lacks necessary substrate, thromboplastin.
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