CET Karnataka Engineering CET - Karnataka Engineering Solved Paper-2003

  • question_answer
    The pH value of gastric juice in human stomach is about 1.8 and in the small intestine it is about 7.8. The \[p{{K}_{a}}\] value of aspirin is 3.5. Aspirin will be:

    A)  completely ionized in the small intestine and in the stomach

    B)  unionised in the small intestine and in the stomach

    C)  ionised in the small intestine and almost unionised in the stomach

    D)  ionised in the stomach and almost unionised in the small, intestine

    Correct Answer: D

    Solution :

    Aspirin is a moderate acid \[(p{{K}_{a}}=3.5)\], hence is almost unionised in stomach due to strong acidic medium of it (because of \[HCl\]). It is due to common ion effect. While in small intestine, the medium is alkaline, hence aspirin will be sufficiently ionised in small intestine.


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