BCECE Medical BCECE Medical Solved Papers-2013

  • question_answer
    Sickle-cell anaemia has not been eliminated from the African population because

    A)  it is controlled by recessive genes

    B)  it is not a fatal disease

    C)  it provides immunity against malaria

    D)  it is controlled by dominant genes

    Correct Answer: B

    Solution :

    Sickle-cell aneamia (in which RBCs become sickle-shaped and stiff) is a genetic disorder that is autosomal and linked to a recessive allele. It has not been eliminated from the African population because it provides immunity against malaria. People who are heterozygous for sickle-cell allelic arc much less susceptible for falciparum malaria/which is one of the main causes of illness and death in them. Thus, the sickle-cell allele is maintained at high levels in populations where falciparum malaria is common.


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