A) Heparin
B) Histamine
C) Serotonin
D) Glucagon
Correct Answer: B
Solution :
The inflammatory process begins with a chemical alarm as a flood of inflammatory chemicals are released into the extra cellular fluid. Injured and stressed tissue cells, phagocytes, lymphocytes, mast cells and blood proteins are all sources of inflammatory mediators, the most important of which are histamine, kinins, prostaglandins and complement. The liberated chemicals increase the permeability of local capillaries, consequently exudate fluid containing clotting factors and antibodies. Heparin the natural anticoagulant. Contained in basophil and mast cell granules is ordinarily secreted in small amounts into the plasma. Like other clotting inhibitors heparin also inhibits the intrinsic pathway. Serotonin is released from the enteroendocrine cells of stomach, diffuse in the blood and ultimately influence several digestive system target organs. Glucagon hormone is secreted from a-cells of islets of Langerhans of pancreas. It causes glycogenolysis and gluconeogenesis.
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