BCECE Medical BCECE Medical Solved Papers-2005

  • question_answer
    Which of the following is not correct about translation?

    A)  It starts with AUG

    B)  Stopped at termination codon

    C)  Based on operon model

    D)  Occurs in nucleus

    Correct Answer: D

    Solution :

    Translation is a process through which the nitrogenous base sequence of m-RNA determines the amino acid sequence of a protein. In prokaryotes and eukaryotes both translation takes place on ribosomes present in cytoplasm. Different amino acids are present in cytoplasm that participate in protein synthesis before their joining together they must be activated by attachment to r-RNA (specific t-RNA). This attachment is accomplished by an amino acid activating enzyme. Each set of three nucleotides of m-RNA is called a codon which specify a single amino acid. The anticodon of t-RNA is complementary to codon of m-RNA and thus form hydrogen bonds between them. When the first t-RNA base pairs with the m-RNA at start codon a second t-RNA molecule moves into position on the second codon. The two amino acids are joined by a peptide bond and the first t-RNA leave the ribosome and pick up another amino acid to continue the polypeptide chain. Any one of three stop codons in the m-RNA signals the end of a polypeptide chain.


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