AMU Medical AMU Solved Paper-1998

  • question_answer
    Glycolysis consists of

    A)  ten enzymatic reactions that convert a six- carbon molecule of four-carbon pyruvate and result in a net gain of 4 ATP molecules

    B)  eight enzymatic reactions that convert a six-carbon molecule to four-carbon pyruvate and result in a net gain of 4 ATP molecules

    C)  ten enzymatic reactions that convert a six- carbon molecules to three-carbon pyruvate and result in a net gain of 4 ATP molecules

    D)  eight enzymatic reactions that convert a six- carbon molecules to three-carbon pyruvate and result in a net gain of 2 ATP molecules.

    Correct Answer: C

    Solution :

    : Glycolysis (Embden Meyerhof Parnas pathway) is the sequence of enzyme catalyzed reactions that converts glucose into two molecules of pyruvate, plus two molecules of NADH with concomitant formation of two ATP molecules. It occurs in the cell cytoplasm. The overall reaction of glycolysis can be summarized as follows - \[\underset{Glucose}{\mathop{{{C}_{6}}{{H}_{12}}{{O}_{6}}}}\,+2NAD+2ADA+\underset{\begin{smallmatrix}  morganic \\  phosphate \end{smallmatrix}}{\mathop{2ip}}\,\xrightarrow[{}]{{}}\] \[\underset{pyruvic\text{ }acid}{\mathop{2C{{H}_{3}}COCOOH}}\,+2NAD{{H}_{2}}+2ATP\] Thus, for each molecule of glucose metabolized by glycolysis there is a net yield of two ATP molecules.


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