• # question_answer Which of the following statements correctly defines Bohr effect? Rise in- A) ${{P}_{50}}\text{ }with\text{ }a\text{ }increases\text{ }in\text{ }C{{O}_{2}}\text{ }cone$B) ${{P}_{60}}\text{ }with\text{ }a\text{ }decreases\text{ }in\text{ }pH$C) $~{{P}_{60}}\text{ }with\text{ }a\text{ }decreases\text{ }in\text{ }pH$D) ${{P}_{50}}\text{ }with\text{ }a\text{ }decreases\text{ }in\,C{{O}_{2}}$

This binding is related to the partial pressure of$C{{O}_{2}}\,.\,pC{{O}_{2}}$ is a major factor which could affect this binding. When $pC{{O}_{2}}$ is high and $p{{O}_{2}}$ is low as in the tissues, more binding of carbon dioxide occurs whereas, when the $pC{{O}_{2}}$ is low and $p{{O}_{2}}$ is high is high as in the alveoli, dissociation of $C{{O}_{2}}$ from carbamino-haemoglobin takes place, i.e., $C{{O}_{2}}$ which is bound to haemoglobin from the tissues is delivered at the alveoli. RBCs contain a very high concentration of the enzyme, carbonic anhydrase and a minute quantity of the same is present in the plasma too.