A) \[{{P}_{50}}\text{ }with\text{ }a\text{ }increases\text{ }in\text{ }C{{O}_{2}}\text{ }cone\]
B) \[{{P}_{60}}\text{ }with\text{ }a\text{ }decreases\text{ }in\text{ }pH\]
C) \[~{{P}_{60}}\text{ }with\text{ }a\text{ }decreases\text{ }in\text{ }pH\]
D) \[{{P}_{50}}\text{ }with\text{ }a\text{ }decreases\text{ }in\,C{{O}_{2}}\]
Correct Answer: A
Solution :
This binding is related to the partial pressure of\[C{{O}_{2}}\,.\,pC{{O}_{2}}\] is a major factor which could affect this binding. When \[pC{{O}_{2}}\] is high and \[p{{O}_{2}}\] is low as in the tissues, more binding of carbon dioxide occurs whereas, when the \[pC{{O}_{2}}\] is low and \[p{{O}_{2}}\] is high is high as in the alveoli, dissociation of \[C{{O}_{2}}\] from carbamino-haemoglobin takes place, i.e., \[C{{O}_{2}}\] which is bound to haemoglobin from the tissues is delivered at the alveoli. RBCs contain a very high concentration of the enzyme, carbonic anhydrase and a minute quantity of the same is present in the plasma too.
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