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Which of the following statements regarding enzyme inhibition is correct?

A)  Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein

B)  Non-competitive inhibitors often bind to the enzyme irreversibly

C)  Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme

D)  Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate