question_answer

A non - hemophilic couple was informed by doctor that there is possibility of a hemophilic child to be born to them. Explain the basis on which doctor conveyed this information. Give the genotype.

Answer:

The doctor conveyed this information on the basis of pedigree analysis. It provides a strong tool through which inheritance of a specific trait, abnormality or disease can be traced.

Since, both the parents are non - haemophilic, the genotype of both will be XY (father) and \[X{{X}^{h}}\] (mother, carrier of disease). Their probability of having a diseased child can be predicted with the help of following cross