question_answer

Study the pedigree chart given above, showing the inheritance pattern of blood groups in a family and answer the following questions.

(i) Give the possible genotypes of the individual 1 and 2.

(ii) Which antigen(s) will be present on the plasma membranes of RBCs of individual 5 and 10?

(iii) Give the genotype of the individuals 3 and 4.

Answer:

(i) Possible genotype and phenotype of individual

\[\begin{matrix}    \text{Genotype} & {} & {} & \text{Phenotype}  \\    \text{Individual}\,\,\text{1} & {{\text{I}}^{\text{A}}}\,{{\text{I}}^{\text{A}}}\,\,\text{or}\,\,{{\text{I}}^{\text{A}}}\text{i} & \to  & \text{Type}\,\text{A}  \\    \text{Individual}\,\,\text{2} & {{\text{I}}^{\text{B}}}\,{{\text{I}}^{\text{B}}}\,\,\text{or}\,\,{{\text{I}}^{\text{B}}}\text{i} & \to  & \text{Type}\,\,\text{B}  \\ \end{matrix}\]

(ii) Individual 5 : Phenotype - AB

Antigen - A and B, Genotype \[-\]\[{{I}^{A}}{{I}^{B}}\]

Individual - 10, Phenotype \[-\]O

Antigen - None, Genotype - ii

(iii) Individual - 3, Phenotype - A

Genotype - \[{{I}^{A}},\,\,{{I}^{A}}\,\,\text{or}\,\,{{I}^{A}}i\]

Individual - 4, Phenotype - B

Genotype - \[{{I}^{B}}{{I}^{B}}\,\,\text{or}\,\,{{I}^{B}}i\]