NEET Biology Molecular basis of Inheritance / विरासत का आणविक आधार Question Bank

done Self Evaluation Test - Molecular Basis of Inheritance Total Questions - 110

• question_answer1)
  DNA polymerisation rate of DNA polymerase is:
  A)
  \[3.9\times {{10}^{7}}bp\]        done clear
  B)
  2000\[bp/s\] done clear
  C)
  \[4.6\times {{10}^{6}}bp\]        done clear
  D)
  5000\[bp/s\] done clear
  View Solution play_arrow

• question_answer2)
  If a nucleotide lacking a hydroxyl group at the 3' end is added to a PCR, what would be the outcome?        
  A)
  No additional nucleotides would be added to a growing strand containing that nucleotide. done clear
  B)
  Strand elongation would proceed as normal. done clear
  C)
  Nucleotides would only be added at the 5' end. done clear
  D)
  T. aquaticus DNA polymerase would be denatured. done clear
  View Solution play_arrow

• question_answer3)
  Which of the following would you expect to find in an inducible system
  A)
  A repressor protein, which is bound to DNA in absence of any other factor. done clear
  B)
  A repressor protein, which is bound to DNA in the presence of a co-repressor. done clear
  C)
  An activator protein, which is bound to D in absence of any other factor. done clear
  D)
  An activator protein, which is bound to DNA only in the absence of an inhibitor. done clear
  View Solution play_arrow

• question_answer4)
  Nonsense codon takes part in:
  A)
  Terminating message of gene controlled protein synthesis. done clear
  B)
  Formation of unspecified amino acids. done clear
  C)
  Conversion of sense DNA into non-sense one. done clear
  D)
  Releasing t RNA from polypeptide chain. done clear
  View Solution play_arrow

• question_answer5)
  Information flow or central dogma of modem biology is:
  A)
  RNA \[\to \] Proteins \[\to \] DNA. done clear
  B)
  DNA \[\to \] RNA \[\to \] Proteins. done clear
  C)
  RNA \[\to \] DNA \[\to \] Proteins. done clear
  D)
  DNA \[\to \] RNA \[\to \] Proteins. done clear
  View Solution play_arrow

• question_answer6)
  AUG initiation codon occurs over:
  A)
  3'end of mRNA done clear
  B)
                     5'end of m RNA done clear
  C)
  Short arm of t RNA                     done clear
  D)
  long arm of t RNA done clear
  View Solution play_arrow

• question_answer7)
  What effect would you expect if gene expression of the lac operon was completely repressed?
  A)
  The cell would be more efficient without wasting' the energy required for the low level of Lac Z, Lac Y, and Lac A gene expression. done clear
  B)
  Allolactose would accumulate within the cell and become toxic. done clear
  C)
  Lactose would not be converted into the inducer and the operon could not be induced. done clear
  D)
  All of the above done clear
  View Solution play_arrow

• question_answer8)
  Identify the correct labelling of A, B, C, D & E.
  A)
  A-Hydrogen bonds, -B-Pyrimidine, C-Hexose (deoxyribose) sugar, D-5' end, E-Purine base done clear
  B)
  A-Hydrogen bonds, B-Purine base, C-Hexose (deoxyribose) sugar,-D-5' end, E-Pyrimidine done clear
  C)
  A-Hydrogen bonds, B-Pyrimidine, C-Pentose (deoxyribose) sugar, D-5' end, E-Purine base done clear
  D)
  A-Hydrogen bonds, B-Purine base, C-Pentose (deoxyribose) sugar, D- 5' end, E- Pyrimidine done clear
  View Solution play_arrow

• question_answer9)
  Given diagram represents the schematic structure of a transcription unit with some parts labeled as A B C and D. Select the option which shows its correct labeling.
  A)

  A	B	C	D
  Terminator	Promoter	Template Strand	Coding Strand

    done clear
  B)

  Promoter

  Terminator

  Coding Strand

  Template Strand

    done clear
  C)

  Promoter

  Terminator

  Template Strand

  Coding Strand

    done clear
  D)

  Terminator

  Promoter

  Coding Strand

  Template Strand

    done clear
  View Solution play_arrow

• question_answer10)
  Which enzymes will be produced in a cell in which there is a nonsense mutation in the lac Y gene?
  A)
  Lactose Permease done clear
  B)
  Transacetylase done clear
  C)
  Lactose permease and transcetylase done clear
  D)
  \[\beta \]-galactosidase done clear
  View Solution play_arrow

• question_answer11)
  SNP which is pronounced as "snips" stands for:
  A)
  Small Nuclear Protein done clear
  B)
  Single Nucleotide Particle done clear
  C)
  Single Nucleotide Polymorphism done clear
  D)
  Small Nicking Points done clear
  View Solution play_arrow

• question_answer12)
  The key finding of the Hershey and Chase experiments on the mechanism of viral replication was that:
  A)
  Protein, not DNA, is the hereditary material. done clear
  B)
  DNA, not protein, is the hereditary material. done clear
  C)
  Protein and DNA play an equal role in determining inheritance. done clear
  D)
  Neither protein nor DNA play a role in determining inheritance. done clear
  View Solution play_arrow

• question_answer13)
  Which of the following is/are correct matching(s)?

  	Codon	Amino acid
  (i)	\[^{5'}AU{{G}^{3'}}\]	Serine
  (ii)	\[^{5'}AU{{C}^{3'}}\]	Tyrosine
  (iii)	\[^{5'}AU{{G}^{3'}}\]	Methionine
  (iv)	\[^{5'}GU{{G}^{3'}}\]	Valine

  A)
  (i) and (iii)                                  done clear
  B)
  All of these done clear
  C)
  (ii), (iii) and (iv)                           done clear
  D)
  (i),(ii) and (iii) done clear
  View Solution play_arrow

• question_answer14)
  Select the two correct statements out of the four (i - iv) given below about lac operon.

  (i) Glucose or galactose may bind with the repressor and inactivate it.

  (ii) In the absence of lactose the repressor binds with the operator region.

  (iii) The z-gene codes for permease.

  (iv) This was elucidated by Francois Jacob and Jacque Monod.

  A)
  (ii) and (iii)                                 done clear
  B)
  (i) and (iii) done clear
  C)
  (ii) and (iv)  done clear
  D)
                     (i) and (ii) done clear
  View Solution play_arrow

• question_answer15)
  Match column-I with column-II and select the correct answer using the codes given below.

  	Column-I		Column-II
  A.	Operator site	I.	Binding site for RNA polymerase
  B.	Promoter site	II.	Binding site for repressor molecule
  C.	Structural gene	III.	Codes for enzyme protein
  D.	Regulator gene	IV.	Codes for repressor molecules

  A)
  A-II;    B-I;     C-III;    D-IV done clear
  B)
  A-II;    B-I;     C-IV;    D-II I done clear
  C)
  A-IV;   B-III;   C-I;      D-II done clear
  D)
  A-II;    B-III;   C-I;      D-IV done clear
  View Solution play_arrow

• question_answer16)
  A bacterium grown over medium having radioactive \[^{35}S\] incorporates radioactivity in:
  A)
  Carbohydrates   done clear
  B)
                     Proteins done clear
  C)
  DNA                                         done clear
  D)
  RNA done clear
  View Solution play_arrow

• question_answer17)
  If a double stranded DNA has 20% of cytosine, what will be the percentage of adenine in it?
  A)
  20%                                          done clear
  B)
  40% done clear
  C)
  30%            done clear
  D)
  60% done clear
  View Solution play_arrow

• question_answer18)
  Chargaff's rules of base pairing states that:
  A)
  The ratio of purines to pyrimidines is roughly equal in all tested organisms. done clear
  B)
  The ratio of A to T is roughly equal in all tested organisms. done clear
  C)
  The ratio of A + T and G + C is roughly equal in all tested organisms. done clear
  D)
  Both [a] and [b] done clear
  View Solution play_arrow

• question_answer19)
  Thirty percent of the bases in a sample of DNA extracted from eukaryotic cells is adenine. What percentage of cytosine is present in this DNA?
  A)
  10%                                          done clear
  B)
  20% done clear
  C)
  30%                                          done clear
  D)
  40% done clear
  View Solution play_arrow

• question_answer20)
  Lac operon is:
  A)
  Arabinose operon done clear
  B)
                     Repressible operon done clear
  C)
  Inducible operon                         done clear
  D)
  Overlapping genes done clear
  View Solution play_arrow

• question_answer21)
  DNA packaging is the way DNA is folded into chromosomes that affects gene expression by:
  A)
  Controlling access to DNA. done clear
  B)
  Positioning related genes near each other. done clear
  C)
  Protecting DNA from mutations. done clear
  D)
  Enhancing recombination of genes. done clear
  View Solution play_arrow

• question_answer22)
  The most common way of gene expression is regulated in both prokaryotes and eukaryotes is through the:
  A)
  Control of mRNA translation. done clear
  B)
  Breakdown of proteins formed by translation. done clear
  C)
  Prevention of DNA uncoiling prior to transcription. done clear
  D)
  Control of gene transcription. done clear
  View Solution play_arrow

• question_answer23)
  Lactose operon produces enzymes:
  A)
  \[\beta \]-galactosidase, permease and glycogen synthetase. done clear
  B)
  \[\beta \]-galactosidase, permease and transacetylase. done clear
  C)
  Permease, glycogen synthetase and transacetylase. done clear
  D)
  \[\beta \]-galactosidase, permease and phosphoglucose isomerase. done clear
  View Solution play_arrow

• question_answer24)
  In negative operon:
  A)
  Co-repressor binds with repressor done clear
  B)
  Co-repressor does not bind with repressor done clear
  C)
  Co-repressor binds with inducer done clear
  D)
  cAMP have negative effect on lac operon done clear
  View Solution play_arrow

• question_answer25)
  Which of the following is the first thing that happens when a signal molecule acts on a target cell?
  A)
  A transcription factor acts on the DNA. done clear
  B)
  The signal molecule binds to RNA. done clear
  C)
  A new protein is made in the target cell. done clear
  D)
  The signal molecule binds to a receptor. done clear
  View Solution play_arrow

• question_answer26)
  Antibiotic inhibiting interaction between t RNA and mRNA during protein synthesis in bacteria is:
  A)
  Tetracycline     done clear
  B)
                     Neomycin done clear
  C)
  Erythromycin    done clear
  D)
                     Streptomycin done clear
  View Solution play_arrow

• question_answer27)
  Which of the following statement forms the basis of DNA fingerprinting?
  A)
  The relative proportions of purines and pyrimidines in DNA. done clear
  B)
  Satellite DNA occurring as highly repeated short DNA segments. done clear
  C)
  The relative difference in the DNA occurrence in blood, skin and saliva. done clear
  D)
  The relative amount of DNA in the ridges and grooves of the fingerprints. done clear
  View Solution play_arrow

• question_answer28)
  Identify the statements pertaining to the regulatory genes (R), associated with the lac operon that are incorrect.

  (i) mRNA is transcribed from the R gene whether lactose is present or not.

  (ii) mRNA is transcribed from the R gene only when the lactose is present.

  (iii) mRNA is transcribed from the R gene only when the lactose is not present.

  (iv) Lactose inhibits the translation or R gene mRNA.

  A)
  (i) and (ii)        done clear
  B)
                     (ii) and (iii) done clear
  C)
  (iii) and (iv)      done clear
  D)
                     (ii), (iii) and (iv) done clear
  View Solution play_arrow

• question_answer29)
  Which one of the following group of codons is called as degenerate codons?
  A)
  UAA, UAG and UGA done clear
  B)
                     GUA, GUG, GCA, GCG and GAA done clear
  C)
                     UUC, UUG, CCU, CAA and CUG done clear
  D)
                     UUA, UUG, CUU, CUC, CUA and CUG done clear
  View Solution play_arrow

• question_answer30)
  Which of the following characters is not associated with a leading strand?
  A)
  Its replication proceeds away from the fork. done clear
  B)
                     Its replication takes place in continuous manner. done clear
  C)
                     Its replication takes place in along 3'-5' direction of template strand. done clear
  D)
                     All of the above. done clear
  View Solution play_arrow

• question_answer31)
  Number of ammo acids in a polypeptide chain   is 150. The number of mRNA bases required is:       given species:          
  A)
  150                                           done clear
  B)
                     450             done clear
  C)
                                        100                                           done clear
  D)
                     50               done clear
  View Solution play_arrow

• question_answer32)
         In a mutational event, when adenine is replaced by guanine, it is a case of:                    
  A)
  Frame shift mutation  done clear
  B)
                     Transcription done clear
  C)
                      Transition   done clear
  D)
                     Transversion          done clear
  View Solution play_arrow

• question_answer33)
              The following ratio is generally constant for a given species:
  A)
  \[\frac{A+G}{C+T}\]                done clear
  B)
                     \[\frac{T+C}{G+A}\] done clear
  C)
                     \[\frac{A+T}{G+C}\] done clear
  D)
                     \[\frac{A+C}{T+G}\] done clear
  View Solution play_arrow

• question_answer34)
  In an eukaryote, a repressor protein may block gene expression by binding to a DNA site called :
  A)
  Operon                                      done clear
  B)
                     Histone done clear
  C)
                     Enhancer done clear
  D)
                     Promoter done clear
  View Solution play_arrow

• question_answer35)
  The given figure shows lac operon model and its functioning. Select the option which correctly labels A, B, X, Y and Z marked in the figure and also identify the label (L) which is primarily responsible for the hydrolysis of the disaccharide, lactose, into galactose & glucose.
  A)

  A	B	X	Y	Z	L
  Repressor	Inducer	\[\beta \]-Galactosidase	Permease	Transacetylase	X

    done clear
  B)
        

  Repressor

  Inducer

  Permease

  \[\beta \]- Galactosidase

  Transacetylase

  Y

    done clear
  C)
        

  Inducer

  Repressor

  \[\beta \]- Galactosidase

  Permease

  Transacetylase

  Z

    done clear
  D)
        

  Inducer

  Repressor

  \[\beta \]- Galactosidase

  Transacetylase

  Permease

  B

    done clear
  View Solution play_arrow

• question_answer36)
  Identify the labels A, B, C and D in the given structure of t RNA and select the correct option.
  A)

  A	B	C	D
  Anticodon loop	\[T\psi C\,loop\]	AA binding site	DHU loop

    done clear
  B)
        

  AA binding site

  \[T\psi C\,loop\]

  Anticodon loop

  DHU loop

    done clear
  C)
        

  AA binding site

  DHU loop

  Anticodon loop

  \[T\psi C\,loop\]

    done clear
  D)
        

  AA binding site

  DHU loop

  \[T\psi C\,loop\]

  Anticodon loop

    done clear
  View Solution play_arrow

• question_answer37)
  Find out the correct statement.
  A)
  Uracil is present in RNA at the place of thymine. done clear
  B)
                     The complex of DNA and protein in chromosome is called chromatin. done clear
  C)
                     Heterochromatin is the most highly condensed form of chromatin. done clear
  D)
                     The process involved in the RNA formation on the DNA template is called replication. done clear
  View Solution play_arrow

• question_answer38)
  DNA fingerprinting using Variable Number Tandem Repeats (VNTRs) is based on the observation that:
  A)
  Every individual has unique alleles at each VNTR locus. done clear
  B)
                     The DNA of VNTR loci is more stable than that of loci which code for proteins. done clear
  C)
                     VNTR sequences show little variability. done clear
  D)
                     VNTR loci are highly polymorphic. done clear
  View Solution play_arrow

• question_answer39)
  Satellite DNA:
  A)
  Is classified in many categories such as micro-satellites, mini satellites, etc. on the basis of base composition length of segments and number of repetitive units. done clear
  B)
                     Normally does not code for any protein. done clear
  C)
                     Shows polymorphism. done clear
  D)
                     All of the above done clear
  View Solution play_arrow

• question_answer40)
  Chargaff's rule is applicable to:
  A)
  Single stranded RNA  done clear
  B)
                         Single stranded DNA and RNA done clear
  C)
                     Single stranded DNA done clear
  D)
                     Double stranded DNA done clear
  View Solution play_arrow

• question_answer41)
  Match the enzymes given in column-I with its function given in column-II and select the correct option.

  	Column-I		Column-II
  A.	\[\beta \]- galactosidase	I.	Joining of DNA fragments
  B.	Permease	II.	Peptide bond formation
  C.	Ligase	III.	Hydrolysis of lactose
  D	Ribozyme	IV.	Increase permeability of galactosidase

  A)
  A-II;    B-I;     C-IV;    D-III done clear
  B)
                     A-III;   B-IV;   C-I;      D-II done clear
  C)
                     A-II;     B-IV;   C-I;     D-III done clear
  D)
                     A-I;     B-II;     C-IV;   D-III done clear
  View Solution play_arrow

• question_answer42)
  Operon is a:
  A)
  Sequence of three nitrogen bases determining a single amino acid. done clear
  B)
                     Set of closely placed genes regulating a metabolic pathway in prokaryotes. done clear
  C)
                     Segment of DNA specifying a polypeptide. done clear
  D)
                     Gene responsible for switching on and switching off other genes. done clear
  View Solution play_arrow

• question_answer43)
  Genes that are involved in turning on or off the transcription of a set of structural genes are called:
  A)
  Operator genes                           done clear
  B)
                     Redundant genes done clear
  C)
                     Regulator genes                           done clear
  D)
                     Polymorphic genes done clear
  View Solution play_arrow

• question_answer44)
  If the gene encoding the trp repressor is mutated such that it can no longer bind to tryptophan, will transcription of the trp operon occur?
  A)
  Yes, because the trp repressor can only bin the trp operon and block transcriptional initiation when it is bound to tryptophan. done clear
  B)
  No, because this mutation does not affect the part of the repressor that can bind the operator. done clear
  C)
  No, because the trp operon is repressed only when tryptophan levels are high. done clear
  D)
  Yes, because the trp operon can allosterically regulate the enzymes needed to synthesise the amino acid tryptophan. done clear
  View Solution play_arrow

• question_answer45)
  Transcriptional regulation:
  A)
  Is highly efficient at completely preventing transcription. done clear
  B)
  Allows the cell to only produce proteins that are needed at the time. done clear
  C)
  Can be induced by a repressor protein. done clear
  D)
  All of the above done clear
  View Solution play_arrow

• question_answer46)
  Post-transcriptional regulation includes:
  A)
  Binding of repressor on silencer regions. done clear
  B)
  Transport of messenger RNA into the cytoplasm. done clear
  C)
  Decreasing messenger RNA stability in the cytoplasm. done clear
  D)
  Both [b] and [c] done clear
  View Solution play_arrow

• question_answer47)
  Mutations which alter nucleotide sequence within a gene are called:
  A)
  Frame shift mutations done clear
  B)
  Base pair substitutions done clear
  C)
  Both [a] and [b] done clear
  D)
  None of the above done clear
  View Solution play_arrow

• question_answer48)
  What would happen if a mutation occurred in the DNA such that the second codon of a polypeptide, UGC, was changed to a UAG?
  A)
  Nothing. The ribosome would skip that codon and translation would continue. done clear
  B)
  Translation would continue, but the reading frame of the ribosome would be shifted. done clear
  C)
  Translation would stop at the second codon and no functional protein would be made. done clear
  D)
  Translation would continue, but the second amino acid in the protein would be different. done clear
  View Solution play_arrow

• question_answer49)
  Which statement is/are correct?

  (i) Nucleosome contains basic protein.

  (ii) Tightly packed DNA of chromatin is called heterochromatin.

  (iii) Loosely packed DNA of chromatin is called euchromatin.

  (iv) \[{{H}_{2}}A,{{H}_{2}}B\] are linker proteins.

  (v) DNA is basic in nature.

  A)
  (i),(ii) and (iii), done clear
  B)
                                 (i) and (ii) done clear
  C)
  (i), (ii), (iii), (iv) and (v) done clear
  D)
  (iv) and (v) done clear
  View Solution play_arrow

• question_answer50)
  Match column-I with column-II and select the correct answer using the codes given below.

  	Column-I		Column-II
  A.	Helicase	I.	Joining of nucleotides
  B.	Gyrase	II.	Opening of DNA
  C.	Primase	III.	Unwinding of DNA
  D.	DNA polymerase	IV.	RNA priming

  A)
  A-II;     B-I;     C-III;    D-IV done clear
  B)
  A-II;     B-I;     C-IV;    D-III done clear
  C)
  A-IV;    B-III;   C-I;      D-II done clear
  D)
  A-II;     B-III;   C-IV;    D-I done clear
  View Solution play_arrow

• question_answer51)
  Which of the following statements about the process of DNA replication is incorrect?
  A)
  Many different enzymes are needed for the process to function properly. done clear
  B)
  Mistakes can be corrected at multiple steps in the process. done clear
  C)
  Uncorrected mistakes introduce mutations into the DNA base sequence. done clear
  D)
  Mistakes in the copying process are very common occurrences. done clear
  View Solution play_arrow

• question_answer52)
  Experiments by Avery, McLeod, and McCarty supported DNA as the genetic material by showing that:
  A)
  Both protein and DNA samples provided the transforming factor. done clear
  B)
  DNA was not complex enough to be the genetic material. done clear
  C)
  Only samples with DNA provided activity. done clear
  D)
  Even though DNA was molecularly simple, it provided adequate variation to act as the genetic material. done clear
  View Solution play_arrow

• question_answer53)
  Enzyme required for removing RNA primer during DNA replication is:
  A)
  Primase                                     done clear
  B)
  Ligase done clear
  C)
  DNA polymerase I                       done clear
  D)
  DNA polymerase III done clear
  View Solution play_arrow

• question_answer54)
  Termination of polypeptide chain is brought about by:
  A)
  UUG                                         done clear
  B)
  UAA done clear
  C)
  UUG                                         done clear
  D)
  UCG done clear
  View Solution play_arrow

• question_answer55)
  Wobble hypothesis establishes:
  A)
  Peptide chain formation done clear
  B)
  Initiation of peptide chain done clear
  C)
  Termination of peptide chain done clear
  D)
  Economy in t RNA molecules. done clear
  View Solution play_arrow

• question_answer56)
  Regulated unit of genetic material is termed as:
  A)
  Operon done clear
  B)
  Regulator gene done clear
  C)
  Operator gene                             done clear
  D)
  Okazaki segment done clear
  View Solution play_arrow

• question_answer57)
  Identify the incorrect statement.
  A)
  In prokaryotes, the structural gene is polycistronic. done clear
  B)
  In eukaryotes, structural genes have interrupted coding sequences. done clear
  C)
  Eukaryotes have split gene arrangement. done clear
  D)
  Intervening sequences appear in mature RNA. done clear
  View Solution play_arrow

• question_answer58)
  Which of the following statements about RNA polymerase are correct?

  (i) RNA polymerase I transcribes rRNAs.

  (ii) RNA polymerase II transcribes snRNAs.

  (iii) RNA polymerase III transcribes hnRNA.

  (iv) RNA polymerase II transcribes hnRNAs.

  A)
  (i) and (ii)                                   done clear
  B)
  (i) and (iii) done clear
  C)
  (ii) and (iii)     done clear
  D)
                     (i) and (iv) done clear
  View Solution play_arrow

• question_answer59)
  The lagging daughter strand of DNA is synthesised in what appears to be the "wrong" direction. This synthesis is accomplished by:
  A)
  Ligating (connecting) short Okazaki fragments that are synthesised in short spurts in the "right" direction. done clear
  B)
  Primase. done clear
  C)
  Using multiple primers and DNA polymerase I. done clear
  D)
  Both [a] and [b] done clear
  View Solution play_arrow

• question_answer60)
  Which of the following factor is required for the protein synthesis?

  (i) Initiation codon

  (ii) GTP and ATP

  (iii) Peptidyl transferase

  (iv) tRNA

  (v) mRNA

  (vi) Amino acid activating enzyme

  (vii) rRNA

  Choose the correct combination.

  A)
  (i), (ii) and (iii) done clear
  B)
                     (iii), (iv) and (v) done clear
  C)
  (v), (vi) and (vii)                         done clear
  D)
  All of these done clear
  View Solution play_arrow

• question_answer61)
  During transcription, the DNA site at which RNA polymerase binds is called:
  A)
  Enhancer       done clear
  B)
                     Promoter done clear
  C)
  Regulator       done clear
  D)
                     Receptor done clear
  View Solution play_arrow

• question_answer62)
  If the nucleus of a frog egg is destroyed and replaced with the nucleus of an intestinal cell from a tadpole, the egg can develop into a normal tadpole. This demonstrates that:
  A)
  Intestinal cells are fully differentiated. done clear
  B)
  There is little functional difference between an egg cell and an intestinal cell. done clear
  C)
  An intestinal cell possesses a full set of genes. done clear
  D)
  Intestinal cells are not differentiated. done clear
  View Solution play_arrow

• question_answer63)
  Which of the following does not play a role in the genetic regulation of tryptophan synthesis in the bacterium E. coli?
  A)
  RNA polymerase done clear
  B)
                     Homeotic gene done clear
  C)
  Repressor protein done clear
  D)
                     Operator done clear
  View Solution play_arrow

• question_answer64)
  Which of the following is most abundant in human DNA?
  A)
  Regulatory genes done clear
  B)
  Non-coding DNA done clear
  C)
  Transposons     done clear
  D)
                     Homeotic genes done clear
  View Solution play_arrow

• question_answer65)
  The regulation of tryptophan synthesis in E. coli is an example of affecting gene expression through:
  A)
  Translational control done clear
  B)
  Transcriptional control done clear
  C)
  Homeotic gene control done clear
  D)
  Breaking down mRNA molecules done clear
  View Solution play_arrow

• question_answer66)
  Isolation and purification of specific DNA segment from a living organism was achieved by:
  A)
  Nirenberg done clear
  B)
  Lederberg done clear
  C)
  Zacharis                                     done clear
  D)
  Watson & Crick done clear
  View Solution play_arrow

• question_answer67)
  Hershey and Chase used radioactive \[^{35}S\] and \[^{32}P\]in experiments to provide evidence that DNA was the genetic material. These experiments pointed to DNA because:
  A)
  Progeny viruses retained \[^{32}P\] but not\[^{35}S\]. done clear
  B)
  Retention of \[^{32}P\] in progeny viruses indicated that DNA was passed on. done clear
  C)
  Loss of \[^{35}S\] in progeny viruses indicated that proteins were not passed. done clear
  D)
  All of the above done clear
  View Solution play_arrow

• question_answer68)
  Histones are rich in:
  A)
  Alanine and glycine done clear
  B)
  Lysine and arginine done clear
  C)
  Histidine and serine done clear
  D)
  Cysteine and tyrosine done clear
  View Solution play_arrow

• question_answer69)
  Which of the following mechanisms of gene regulation operates after mRNA transcription but before translation of mRNA into protein?
  A)
  mRNA splicing   done clear
  B)
  DNA packing       done clear
  C)
  Repressors and activators done clear
  D)
  Protein degradation done clear
  View Solution play_arrow

• question_answer70)
  The process of the elongation in transcription requires:
  A)
  \[C{{a}^{++}}\,or\,M{{n}^{++}}\] done clear
  B)
                     \[N{{a}^{+}}\,or\,C{{l}^{-}}\] done clear
  C)
  \[N{{a}^{+}}\,or\,{{K}^{+}}\]          done clear
  D)
  \[M{{n}^{++}}\,or\,M{{g}^{+2}}\] done clear
  View Solution play_arrow

• question_answer71)
  DNA replication is:
  A)
  Conservative and discontinuous. done clear
  B)
  Semi-conservative and semi-discontinuous. done clear
  C)
  Semi-conservative and discontinuous; done clear
  D)
  conservative done clear
  View Solution play_arrow

• question_answer72)
  DNA binding proteins:
  A)
  Have distinct three-dimensional structures that allow them to bind to the DNA. done clear
  B)
  Are transcription factors. done clear
  C)
  Inhibit the loss of ends from the chromosome and help DNA condense in the nucleus. done clear
  D)
  All of the above done clear
  View Solution play_arrow

• question_answer73)
  A short sequence of bases on one strand of DNA is AGTCTACCGATAGT. If this sequence serves as a template for the formation of a new strand of DNA, what will be the corresponding base sequence in the new strand?
  A)
  AGTCTACCGATAGT done clear
  B)
  TCAGATGGCTATCA done clear
  C)
  TGATAGCCATCTGA done clear
  D)
  GACATCGATTCGAT done clear
  View Solution play_arrow

• question_answer74)
  DNA replication is semi-conservative as:
  A)
  Only non-parent strand acts as template. done clear
  B)
  Both strands of new molecule are synthesized de novo. done clear
  C)
  One of the strand in each new molecule is parental and the other is new. done clear
  D)
  Daughter strands are dispersive. done clear
  View Solution play_arrow

• question_answer75)
  Chromatin structure must be altered in order for gene expression to occur because:
  A)
  Condensed chromatin is replicated but not transcribed. done clear
  B)
  Condensed chromatin makes most DNA sequence inaccessible to the transcription complex. done clear
  C)
  Decondensed   chromatin   has   more nucleosomes per DNA molecule. done clear
  D)
  Heterochromatin is actively transcribed and euchromatin is not transcribed. done clear
  View Solution play_arrow

• question_answer76)
  Introns are DNA sequences that:
  A)
  Code for functional domains in proteins. done clear
  B)
  Are removed from pre-mRNA by spliceosomes. done clear
  C)
  Allow one gene to make different gene products depending on which introns are removed during splicing done clear
  D)
  Both [b] and [c] done clear
  View Solution play_arrow

• question_answer77)
  Transcription:
  A)
  Starts at initiator region and ends at stop region. done clear
  B)
  Starts at operator region and ends at telomeric end. done clear
  C)
  Starts at promoter region and ends terminator region. done clear
  D)
  Starts at CAAT box and ends at TATA box. done clear
  View Solution play_arrow

• question_answer78)
  Match column-I with column-II and choose the correct option.

  	Column-I		Column-II
  A.	Exon	I.	Coding sequence
  B.	Intron	II.	Cistron
  C.	Genetic code	III.	Triplet bases on mRNA
  D.	DNA packaging	IV.	Nucleosome
  E.		V.	Non-codding sequence

  A)
  A-I;      B-III;      C-II;    D-V done clear
  B)
  A-I;      B-IV;     C-II;     D-III done clear
  C)
  A-I;       B-V;      C-III;   D-IV done clear
  D)
  A-IV;    B-I;       C-V;    D-III done clear
  View Solution play_arrow

• question_answer79)
  Choose the sequence in which the following enzymes take part in DNA replication.

  (i) Helicase

  (ii) Primase

  (iii) SSB

  (iv) DNA polymerase

  (v) DNA ligase

  A)
  (i) \[\to \] (v) \[\to \] (iv) \[\to \] (iii) \[\to \] (ii) done clear
  B)
  (i) \[\to \] (ii) \[\to \] (iii) \[\to \] (iv) \[\to \] (v) done clear
  C)
  (i) \[\to \] (iii) \[\to \] (ii) \[\to \] (iv) \[\to \] (v) done clear
  D)
  (i) \[\to \] (iv) \[\to \] (iii) \[\to \] (ii) \[\to \] (v) done clear
  View Solution play_arrow

• question_answer80)
  Code transfer for synthesis of polypeptide involves:              
  A)
  DNA, tRNA, rRNA and mRNA. done clear
  B)
  mRNA, tRNA, rRNA and DNA. done clear
  C)
  tRNA, DNA, mRNA and rRNA. done clear
  D)
  DNA, mRNA, tRNA and amino acids. done clear
  View Solution play_arrow

• question_answer81)
  Eukaryotic chromosomes:
  A)
  Are circular and contain origin and terminator sequences. done clear
  B)
  Are linear and have origins and telomeres. done clear
  C)
  Contain coding and non-coding sequences. done clear
  D)
  Both [b] and [c] done clear
  View Solution play_arrow

• question_answer82)
  DNA is a genetic material:

  (i) Due to its stability.

  (ii) Its ability to replicate.

  (iii) Its ability to mutate.

  (iv) Its ability to express itself.

  Choose the correct combination.

  A)
  (i) and (ii)                                   done clear
  B)
  (i), (iii) and (iv) done clear
  C)
  (iii) and (iv)                                done clear
  D)
  (i), (ii), (iii) and (iv) done clear
  View Solution play_arrow

• question_answer83)
  tRNA recognises ribosome by:
  A)
  \[T\psi C\,\,loop\]   done clear
  B)
                     DHU loop done clear
  C)
  Anticodon       done clear
  D)
                     AA-site done clear
  View Solution play_arrow

• question_answer84)
  Nucleotide arrangement in DNA can be seen by:
  A)
  X-ray crystallography done clear
  B)
  Electron microscope done clear
  C)
  Ultracentrifuge                            done clear
  D)
  Light microscope done clear
  View Solution play_arrow

• question_answer85)
  DNA synthesis can be measured by estimating incorporation of radio-labeled:
  A)
  Uracil                                        done clear
  B)
  Ribose sugar done clear
  C)
  Thymidine  done clear
  D)
                     Adenine done clear
  View Solution play_arrow

• question_answer86)
  During conjugation:
  A)
  DNA from one bacterial cell is transferred to another bacterial cell using a bacteriophage. done clear
  B)
  Mutants that are auxotrophic for one nutrient can be converted to prototrophs when mixed with mutants that are auxotrophic for another nutrient. done clear
  C)
  A pilus is synthesised and DNA is transferred from one bacterium across the conjugation tube to the recipient bacterium. done clear
  D)
  Both [a] and [b] done clear
  View Solution play_arrow

• question_answer87)
  Transposable genetic elements:
  A)
  Always affect the cell adversely, because when they move, they inactivate genes. done clear
  B)
  Are retroviruses. done clear
  C)
  Provide a mechanism for moving genetic material from organelle genomes to the nuclear genome. done clear
  D)
  Always replicate their DNA when they want. done clear
  View Solution play_arrow

• question_answer88)
  The scientists involved in discovery of DNA as chemical basis of heredity were:
  A)
  Hershey and Chase done clear
  B)
  Griffith and Avery done clear
  C)
  Avery, Mac Leod and McCarty done clear
  D)
  Watson and Crick done clear
  View Solution play_arrow

• question_answer89)
  Match column-I with column-II and select the correct combination from the given options.

  	Column-I		Column-II
  A.	Sigma factor	I.	5?-3?
  B.	Capping	II.	Initiation
  C.	Tailing	III.	Termination
  D.	Codding strand	IV.	5? end
  		V.	3?end

  A)
  A-III;    B-V;    C-IV;   D-II done clear
  B)
  A-II;     B-IV;   C-V;    D-I done clear
  C)
  A-II;      B-IV;   C-V;    D-III done clear
  D)
  A-III;     B-V;    C-IV;   D-I done clear
  View Solution play_arrow

• question_answer90)
  Select the incorrect statement(s) about genetic codon.

  (i) Six codons do not code for any amino acid.

  (ii) Codon is read in mRNA in a contiguous fashion.

  (iii) Three codons function as stop codons.

  (iv) The initiation codon AUG codes for methionine.

  A)
  (i) only        done clear
  B)
                     (ii) only done clear
  C)
  (i), (ii) and (iv)   done clear
  D)
                     (i), (ii) and (iii) done clear
  View Solution play_arrow

• question_answer91)
  Match column-I with column-II and select the correct answer using the codes given below.

  	Column-I		Column-II
  A.	Termination	I.	Aminoacyl tRNA synthetase
  B.	Translation	II.	Okazaki fragments
  C.	Transcription	III.	GTP dependent release factor
  D.	DNA replication	IV.	RNA polymerase

  A)
  A-II;   B-I;      C-III;   D-IV done clear
  B)
                     A-III;   B-I;     C-IV;   D-II done clear
  C)
                     A-IV;   B-III;   C-I;     D-II done clear
  D)
                     A-II;    B-III;   C-I;     D-IV done clear
  View Solution play_arrow

• question_answer92)
  Co-repressor binds with:     
  A)
  Promoter gene                            done clear
  B)
                     Operator gene done clear
  C)
                     Aporepressor                              done clear
  D)
                     Regulator gene done clear
  View Solution play_arrow

• question_answer93)
  In lac operon, structural gene 'z' synthesises:
  A)
  \[\beta \]-galactosidase done clear
  B)
                     Galactosidase permease done clear
  C)
                     Galactosidase transacetylase done clear
  D)
  None of the above done clear
  View Solution play_arrow

• question_answer94)
  E.coli cells with a mutated z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because:
  A)
  The lac operon is constitutively active in these cells. done clear
  B)
                     They cannot synthesise functional beta- galactosidase. done clear
  C)
                     In the presence of glucose, E.coli cells do not utilize lactose. done clear
  D)
                     They cannot transport lactose from the medium into the cell. done clear
  View Solution play_arrow

• question_answer95)
  Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in protein synthesis or as 'start' or 'stop' codon?
  A)
  UAC-Tyrosine                             done clear
  B)
                     UCG-Start done clear
  C)
                     UUU-Stop                                  done clear
  D)
                     UGU-Leucine done clear
  View Solution play_arrow

• question_answer96)
  Which step of translation does not consume a high energy phosphate bond?
  A)
  Translocation           done clear
  B)
                     Amino acid activation done clear
  C)
                     Peptidyl-transferase reaction done clear
  D)
                     Aminoacyl tRNA binding to active ribosomal site done clear
  View Solution play_arrow

• question_answer97)
  One gene one enzyme hypothesis was proposed by:
  A)
  Khorana and Nirenberg done clear
  B)
                     Beadle and Tatum done clear
  C)
                     Bateson and Punnet done clear
  D)
                     Bridges done clear
  View Solution play_arrow

• question_answer98)
  In some viruses, RNA is present instead of DNA indicating that:
  A)
  Their nucleic acid must combine with host DNA before replication. done clear
  B)
                     They cannot replicate. done clear
  C)
                     There is no hereditary information. done clear
  D)
                     RNA can act to transfer heredity. done clear
  View Solution play_arrow

• question_answer99)
  What is the main function of tRNA in relation to protein synthesis?
  A)
  Initiates transcription done clear
  B)
                     Inhibits protein synthesis. done clear
  C)
                     Identifies amino acids and transport them to ribosomes. done clear
  D)
                     Proofreading. done clear
  View Solution play_arrow

• question_answer100)
  In tertiary structure of DNA, what is a histone octamer?          
  A)
  A complex consisting of eight positively charged histone proteins (two of each\[{{H}_{2}}A,{{H}_{2}}B,{{H}_{3}}and{{H}_{4}}\]) that aid in the packaging of DNA. done clear
  B)
                     A complex consisting of eight negatively charged histone proteins (two of each\[{{H}_{2}}A,{{H}_{2}}B,{{H}_{3}}and{{H}_{4}}\]) that aid in the packaging of DNA. done clear
  C)
                     A complex consisting of nine positively charged histone proteins (\[{{H}_{1}}\]and two of each\[{{H}_{2}}A,{{H}_{2}}B,{{H}_{3}}and{{H}_{4}}\]) that aid in the packaging DNA. done clear
  D)
                     A complex consisting of nine negatively charged histone proteins (v\[{{H}_{1}}\] and two of each\[{{H}_{2}}A,{{H}_{2}}B,{{H}_{3}}and{{H}_{4}}\]) that aid in the packaging of DNA. done clear
  View Solution play_arrow

• question_answer101)
  Phosphodiester linkage is formed between:
  A)
  C-5 of one nucleotide and C-3 of the next done clear
  B)
                     C-1 of one nucleotide and C-2 of the next done clear
  C)
                     Purines of opposite strands done clear
  D)
                     Pyrimidines of opposite strands done clear
  View Solution play_arrow

• question_answer102)
  From the experiments carried out by Avery, Macleod and McCarty by using various enzymes, which of the following results prominently proved that DNA is the transforming material?
  A)
  DNA of heat killed 'S' + R type + DNAase \[\to \]virulent strain done clear
  B)
                     DNA of heat killed 'S'+R type + RNAase \[\to \]virulent strain done clear
  C)
                     DNA of heat killed' S' + R type\[\to \]virulent strain done clear
  D)
                     DNA of heat killed 'S'+R type + Protease\[\to \]virulent strain done clear
  View Solution play_arrow

• question_answer103)
  A segment of DNA molecule contains 200 guanine and 200 thymine bases. What will be the total number of nucleotides in this segment of DNA?
  A)
  400                                           done clear
  B)
                     200 done clear
  C)
                     800             done clear
  D)
                     100 done clear
  View Solution play_arrow

• question_answer104)
  In ABO system of blood group there are 4-types of:
  A)
  Genotypes                                 done clear
  B)
                     phenotypes done clear
  C)
                     Antibodies                                  done clear
  D)
                     alleles done clear
  View Solution play_arrow

• question_answer105)
  During elongation of polypeptide chain, sigma factor is:               
  A)
  Functionless. done clear
  B)
                     Retained for specific function. done clear
  C)
                     Released for re-use. done clear
  D)
                     Required during closing of chain. done clear
  View Solution play_arrow

• question_answer106)
  Genetic code is:
  A)
  Triplet, universal, ambiguous and degenerate. done clear
  B)
                     Triplet, universal, non-ambiguous and non- degenerate. done clear
  C)
                     Triplet, universal, non-ambiguous and degenerate. done clear
  D)
                     Triplet, universal, ambiguous and non- degenerate. done clear
  View Solution play_arrow

• question_answer107)
  Plasmid DNA contains genes that:
  A)
  Confer drug resistance to the host cell. done clear
  B)
                     Regulate conjugation. done clear
  C)
                     Can confer resistance to heavy metals. done clear
  D)
                     All of the above done clear
  View Solution play_arrow

• question_answer108)
  Who gave the 1st experimental proof of triplet code?
  A)
  George Gamow                          done clear
  B)
                     Nirenberg done clear
  C)
                     Kohenberg                                  done clear
  D)
                     Khorana done clear
  View Solution play_arrow

• question_answer109)
  Methyl guanosine triphosphate is added at 5' end of hn RNA in a process of:
  A)
  Tailing                                       done clear
  B)
                     Splicing done clear
  C)
                     Capping      done clear
  D)
                     None of these done clear
  View Solution play_arrow

• question_answer110)
  The given figure represent one of the step in the process of transcription in bacteria. Identify the step and label A, B & C marked in the figure.
  A)
  Initiation; A - DNA, B - RNA, C - Promoter done clear
  B)
                     Termination; A - RNA, B - RNA polymerase, C - Rho factor done clear
  C)
                     Elongation; A - RNA, B - RNA polymerase, C - Sigma factor done clear
  D)
                     Elongation; A-DNA, B - DNA polymerase, C - RNA done clear
  View Solution play_arrow