NEET Biology Molecular basis of Inheritance / विरासत का आणविक आधार Question Bank

done Topic Test - Molecular Basis of Inheritance (18-5-21) Total Questions - 60

• question_answer1)
  The chemical nature of a gene is
  A)
  protein done clear
  B)
  acid done clear
  C)
  base done clear
  D)
  none of these done clear
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• question_answer2)
  Number of base pairs in DMA helix around the octamer histone molecule is
  A)
  140 - 200 bp      done clear
  B)
  100 -150 bp done clear
  C)
  40 - 67 bp done clear
  D)
  200 - 260 bp done clear
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• question_answer3)
  International Human Genome Project began in
  A)
  1990 done clear
  B)
  1996 done clear
  C)
  2000     done clear
  D)
  2001 done clear
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• question_answer4)
  Chargaff’s rules of base pairing states that
  A)
  The ratio of purines to pyrimidines is roughly equal in all tested organisms. done clear
  B)
  The ratio of A to T is roughly equal in all tested organisms. done clear
  C)
  The ratio of A + T and G + C is roughly equal in all tested organisms. done clear
  D)
  a and b done clear
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• question_answer5)
  Watson and Crick's model allowed them to visualize
  A)
  The molecular bonds of DNA done clear
  B)
  How the purines and pyrimidines fit together in a double helix. done clear
  C)
  That the two strands of the DNA double helix were antiparallel. done clear
  D)
  All of the above done clear
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• question_answer6)
  The primary function of DNA polymerase is to
  A)
  Add nucleotides to the growing daughter strand. done clear
  B)
  Seal nicks along the sugar-phosphate backbone of the daughter strand. done clear
  C)
  Unwind the parent DNA double helix. done clear
  D)
  Prevent reassociation of the denatured parent DNA strands. done clear
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• question_answer7)
  Proofreading and repair occur
  A)
  At anytime during or after synthesis of DNA done clear
  B)
  Only before DNA methylation occurs. done clear
  C)
  Only in the presence of DNA polymerase. done clear
  D)
  Only in the presence of an excision repair mechanism. done clear
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• question_answer8)
  DNA replication is an ______ process and _________ energy.
  A)
  Exergonic; does not require done clear
  B)
  Endothermic; does require done clear
  C)
  Endergonic; does require done clear
  D)
  Endodontic; does not require done clear
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• question_answer9)
  Which of the following would not be found in a DNA molecule?
  A)
  Purines done clear
  B)
  Sugars done clear
  C)
  Phosphates done clear
  D)
  Sulfur done clear
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• question_answer10)
  Which statement about complementary base pairing is not true?
  A)
  It plays a role in DNA replication done clear
  B)
  In DNA, T pairs with A done clear
  C)
  Purines pair with purines, and pyrimidines pair with pyrimidines. done clear
  D)
  In DNA, C pairs with G. done clear
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• question_answer11)
  The leading strand and lagging strand in DNA replication differ in that only on the lagging strand
  A)
  DNA is replicated as short fragments. done clear
  B)
  RNA primer is present, done clear
  C)
  Replication proceeds in the 5' to 3' direction done clear
  D)
  DNA ligase is not needed. done clear
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• question_answer12)
  How many adenylate residues are added at 3' end during the processing of hnRNA in eukaryotes?
  A)
  50-100 done clear
  B)
  100-150 done clear
  C)
  600-700 done clear
  D)
  200-300 done clear
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• question_answer13)
  Which of the following model organisms has been sequenced?
  A)
  Drosophila done clear
  B)
  Bacteria done clear
  C)
  Yeast done clear
  D)
  All done clear
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• question_answer14)
  nu body of nucleosome consists of
  A)
  \[{{H}_{1}}\]and \[{{H}_{2}}A\] done clear
  B)
  (b \[{{H}_{2}}A\] and \[{{H}_{2}}B\] done clear
  C)
  \[{{H}_{3}}\] and \[{{H}_{4}}\] done clear
  D)
  Both [b] & [c] done clear
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• question_answer15)
  Which one of the following is used as marker chromosome?
  A)
  Monocentric chr. done clear
  B)
  SAT-chromosome done clear
  C)
  Idiosome done clear
  D)
  chromosome done clear
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• question_answer16)
  HOP methodology which includes identification of all the genes that expressed as RNA is referred as
  A)
  RFLP done clear
  B)
  ESTs done clear
  C)
  VNTR done clear
  D)
  RAPD's done clear
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• question_answer17)
  The last human chromosome which sequence was completed in May 2006 is
  A)
  Chromosome 22 done clear
  B)
  Chromosome 1 done clear
  C)
  Chromosome 1 done clear
  D)
  Chromosome X and Y done clear
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• question_answer18)
  Separation of DNA fragments into bands by electrophoresis is done on
  A)
  Agarose gel done clear
  B)
  Polyacrylamide gel done clear
  C)
  Arabic gum done clear
  D)
  Both [a] and [b] done clear
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• question_answer19)
  Enzyme utilised for the synthesis of RNA copolymers and homopolymers during deciphering of genetic code is-
  A)
  DNA dependent RNA polymerase done clear
  B)
  RNA dependent DNA polymerase done clear
  C)
  DNA independent RNA polymerase done clear
  D)
  DNA dependent DNA polymerase done clear
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• question_answer20)
  The entire genetic code consists of __ amino acids and __ codons.
  A)
  20, 20 done clear
  B)
  20, 64 done clear
  C)
  30, 60 done clear
  D)
  30, 72 done clear
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• question_answer21)
  Which mode of information transfer usually does not occur?
  A)
  DNA to DNA done clear
  B)
  DNA to RNA done clear
  C)
  DNA to protein done clear
  D)
  All occur in a working cell done clear
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• question_answer22)
  Which of the following is not the characteristic feature of genetic code
  A)
  Triplet in nature done clear
  B)
  Mostly universal done clear
  C)
  Ambiguous done clear
  D)
  Degeneracy done clear
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• question_answer23)
  Which one of the following is a wrong statement regarding mutations?
  A)
  Deletion and insertion of base pairs cause frame-shift mutations done clear
  B)
  Cancer cells commonly show chromosomal aberrations done clear
  C)
  UV and Gamma rays are mutagens done clear
  D)
  Change, in a single base pair of DNA does not cause mutation done clear
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• question_answer24)
  What is it that forms the basis of DNA Fingerprinting?
  A)
  The relative proportions of purines and pyrimidines in DNA done clear
  B)
  The relative difference in the DNA occurrence in blood, skin and saliva done clear
  C)
  The relative amount of DNA in the ridges and grooves of the fingerprints. done clear
  D)
  Satellite DNA occurring as highly repeated short DNA segments done clear
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• question_answer25)
  Crick, one of the discoverer of DNA double helical structure, was the man of
  A)
  Physics done clear
  B)
  Chemistry done clear
  C)
  Zoology done clear
  D)
  Botany done clear
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• question_answer26)
  The number of codons that code different amino acids is -
  A)
  16 done clear
  B)
  31        done clear
  C)
  61 done clear
  D)
  64 done clear
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• question_answer27)
  Out of 64 codons, the number of codons with GGG is
  A)
  1 done clear
  B)
  2           done clear
  C)
  4 done clear
  D)
  6 done clear
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• question_answer28)
  If one strand of DNA has the nitrogenous base sequence at ATCTG, what would be the complementary RNA strand sequence
  A)
  TTAGU done clear
  B)
  UAGAC done clear
  C)
  AACTG done clear
  D)
  ATCGU done clear
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• question_answer29)
  Removal of introns and joining of exons in a defined order during transcription is called:
  A)
  Looping done clear
  B)
  Inducing done clear
  C)
  Slicing done clear
  D)
  Splicing done clear
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• question_answer30)
  The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C.
  A)
  A-translation, B-transcription, C-Erwin Chargaff done clear
  B)
  A-transcription, B-translation, C-Francis Crick done clear
  C)
  A-translation, B-extension, C-Rosalind Franklin done clear
  D)
  A-transcription, B-replication, C-James Watson done clear
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• question_answer31)
  Nucleosome consist of repeated unit of structure in nucleus called
  A)
  Chromatin done clear
  B)
  Chromosome done clear
  C)
  Histone octamer done clear
  D)
  Nucleotide done clear
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• question_answer32)
  Which of the following pairs is incorrectly matched?
  A)
  Purines - Adenine and Guanine done clear
  B)
  Pyrimidines - Cytosine and Uracil done clear
  C)
  Nucleosides - Adenosine and Thymidine done clear
  D)
  DNA - Basic biomolecule done clear
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• question_answer33)
  In nucleotide molecule, nitrogenous base is linked to pentose sugar by ‘A’ linkage and the pentose sugar is linked to phosphate by ‘B’ linkage. Identify A and B.
  A)

  	Column A	Column B
  	N - Glycosidic linkage	Amide linkage

  done clear
  B)

  N - Glycosidic linkage

  Phosphodiester linkage

  done clear
  C)

  Phosphodiester linkage

  Amide linkage

  done clear
  D)

  Amide linkage

  Phosphodiester linkage

  done clear
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• question_answer34)
  Semi - conservative nature of DNA experiment given by
  A)
  Marshey and Chase done clear
  B)
  Alfred Hershey and Martha Chase done clear
  C)
  Matthew Meselson and Franklin Stahl done clear
  D)
  MacLoad and Maclyn MacCarty done clear
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• question_answer35)
  If the DNA of a vims is labelled with \[^{32}P\] and the protein of the virus is labelled \[^{35}S\], after transduction which molecule (s) would be present inside the bacterial cells?
  A)
  \[^{32}P\] only done clear
  B)
  \[^{35}S\] only done clear
  C)
  Both "S and32? done clear
  D)
  (d Neither molecule would be present inside the cell done clear
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• question_answer36)
  Which of the following statement is incorrect?
  A)
  Both DNA and RNA are able to mutate. done clear
  B)
  Griffith's transforming principle also explained the stability of genetic material. done clear
  C)
  DNA chemically is less reactive and structurally more stable. done clear
  D)
  RNA is passed from vims to bacteria. done clear
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• question_answer37)
  Larger submit ofribosome contains:
  A)
  Gyrase done clear
  B)
  Peptidyl transferal done clear
  C)
  Topoisomerase done clear
  D)
  RNA - polymerase done clear
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• question_answer38)
  Okazaki fragments during DNA replication:
  A)
  Polymerise in \[5'\to 3'\] direction and explain \[3'\to 5'\]DNA replication done clear
  B)
  Prove semiconservative DNA replication done clear
  C)
  Polymerase in \[3'\to 5'\] direction and replication fork done clear
  D)
  Cause transcription done clear
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• question_answer39)
  The discontinuously synthesized fragments are joined by the enzyme
  A)
  DNA ligase done clear
  B)
  DNA polymerase done clear
  C)
  Helicase done clear
  D)
  Lyase done clear
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• question_answer40)
  DNA unwinding is done by
  A)
  Ligase done clear
  B)
  Helicase done clear
  C)
  Topoisomerase done clear
  D)
  Hexonuclease done clear
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• question_answer41)
  Coding sequence which appear in mature RNA is
  A)
  Exon done clear
  B)
  Intron done clear
  C)
  Cistron done clear
  D)
  Splicing done clear
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• question_answer42)
  Capping is a process in which
  A)
  Adenylate is added at 5’ end done clear
  B)
  Methyl guanosine triphosphate is added at 5’ end done clear
  C)
  Adenylate is added at 3’ end done clear
  D)
  Methyl guanosine triphosphate is added at 3’ end done clear
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• question_answer43)

  Given diagram represents the components of a transcription unit. Select the correct answer regarding it.

  A)

  	A	B	C	D
  	Terminator	Promoter	Template strand	Coding strand

  done clear
  B)

  Promoter

  Terminator

  Coding strand

  Template strand

  done clear
  C)

  Promoter

  Terminator

  Template strand

  Coding strand

  done clear
  D)

  Terminator

  Promoter

  Coding strand

  Template strand

  done clear
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• question_answer44)
  Select the incorrectly matched pair
  A)
  Initiation Codons            -   AUG, GUG done clear
  B)
  Stop codons                   -   UAA, UAG, UGA done clear
  C)
  Methionine        -   AUG done clear
  D)
  Anticodons        -   mRNA done clear
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• question_answer45)
  Reverse transcriptase:
  A)
  Transcribes viral RNA to cDNA done clear
  B)
  Polymerises host DNA done clear
  C)
  Translates host DNA done clear
  D)
  Disintegrates host DNA done clear
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• question_answer46)
  Match the column -1 with column - II

  Column - I (Process)	Column - II (Enzyme involved)
  A. Termination	DNA polymerase
  B. Translation	Peptidyl transferase
  C. Transcription	Reverse transcription
  D. Replication	RNA polymerase

  A)
  A - 2    B - 4      C - 1     D - 3     E - 5 done clear
  B)
  A - 4    B - 2      C - 1     D - 3     E - 5 done clear
  C)
  A - 3    B - 2      C - 5     D - 4     E - 1 done clear
  D)
  A - 4   B - 3       C - 5     D - 2     E - 1 done clear
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• question_answer47)
  Frame shift mutations are caused by
  A)
  Inversion and translocation done clear
  B)
  Deletion and insertion done clear
  C)
  Deletion and transversion done clear
  D)
  Insertion and inversion done clear
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• question_answer48)
  Gene capable of moving from the chromosome to another is:
  A)
  Cosmid done clear
  B)
  Transposon done clear
  C)
  Exonic gene done clear
  D)
  Mutated gene done clear
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• question_answer49)
  The process of translation is:
  A)
  Ribosome synthesis done clear
  B)
  RNA synthesis done clear
  C)
  DNA synthesis done clear
  D)
  Protein synthesis done clear
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• question_answer50)
  Polymorphism is
  A)
  Variation at cellular level done clear
  B)
  Variation at chromosomal level done clear
  C)
  Variation at genetic level done clear
  D)
  None of the above done clear
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• question_answer51)
  The sequence of a structural gene in lac operon is
  A)
  lac a, lac y and lac z done clear
  B)
  lac a, lac z and lac y done clear
  C)
  lac y, lac z and lac a done clear
  D)
  lac z, lac y and lac a done clear
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• question_answer52)
  Which of the following in not produced by E. coli in the lac operon?
  A)
  \[\beta \] galactosidase done clear
  B)
  Thiogalactoside transacetylase done clear
  C)
  Lactose dehydrogenase done clear
  D)
  Lactose permease done clear
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• question_answer53)
  The inducer of lac operon is
  A)
  Permease done clear
  B)
  Lactose done clear
  C)
  Galactose done clear
  D)
  Transacetylase done clear
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• question_answer54)
  The commonly used hosts in HOP were
  A)
  Bacteria and yeast done clear
  B)
  Bacteria and fungi done clear
  C)
  Protozoa and bacteria done clear
  D)
  Plants and fungi done clear
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• question_answer55)
  DNA fingerprinting technique was developed by:
  A)
  Boysen and Jensen done clear
  B)
  Schleiden and Schwann done clear
  C)
  Jeffreys et al done clear
  D)
  Edwards and Steptoe done clear
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• question_answer56)
  Which of the following correctly describes chromatin?
  A)
  The complex of DNA and protein from which chromosomes are composed. done clear
  B)
  the total genetic content of a cell. done clear
  C)
  The proteins that give structural support to a done clear
  D)
  Unpacked DNA done clear
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• question_answer57)

  Match the column and find out the correct combination:

  Gene Product Function of the product I. z-gene \[\beta \]-galactosidase Hydrolysis lactose II. y-gene Transacetylase Uptake of lactose III. a-gene Permease protein Function not known IV. Inhibitor gene Repressor protein Switch off operator gene

  A)
  II and III done clear
  B)
  I and III done clear
  C)
  I, III, IV done clear
  D)
  I and IV done clear
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• question_answer58)
  Select the incorrect statement about lac operon when lactose is present in the medium.
  A)
  Gene a gets transcribed into mRNA which produces \[\beta \]-galactosidepermease done clear
  B)
  Lactose inactivates represser protein done clear
  C)
  RNA polymerase transcribe z-gene, y-gene and a-gene done clear
  D)
  Allolactose is the inducer of lac operon done clear
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• question_answer59)
  Consider the following statement w.r.t. human genome project and select the wrong choice.
  A)
  Scientists have identified about 1.4 million locations where SNPs occur. done clear
  B)
  The human genome contains 3164.7 billion nucleotide base. done clear
  C)
  The total number of genes is estimated at 30,000. done clear
  D)
  Less than 2 percent of the genome codes for proteins. done clear
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• question_answer60)
  In E. coli, rho—factor is required for:
  A)
  Initiation of transcription at specific site done clear
  B)
  Initiation of transcription at many site done clear
  C)
  Termination of transcription at specific site done clear
  D)
  Termination of transcription at many sites done clear
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