question_answer 1)
Genetic engineering is the
A)
Formation of new gene artificially done
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B)
Formation of RNA from DNA artificially done
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C)
Modification of genes artificially done
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D)
Formation of DNA from non DNA material done
clear
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question_answer 2)
Genetically engineered insulin can be obtained by
A)
Recombinant DNA technique with the help of E. coli done
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B)
Two coded insulin genes separated then incorporated into bacteria done
clear
C)
The extraction of cow's and pig's pancreas done
clear
D)
Technique not developed till now done
clear
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question_answer 3)
Trade name of genetically engineered insulin is
A)
Anulin done
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B)
Beta insulin done
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C)
Humilin done
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D)
Gilbert's insulin done
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question_answer 4)
Somatostatin or human growth hormone (HGH) for the first time was genetically isolated by
A)
Benting and Best done
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B)
Ross done
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C)
Pasteur done
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D)
Goeddel done
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question_answer 5)
Goeddel and his associates biosynthesised the HGH by genetic engineering by
A)
RNA incorporation into E. coli done
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B)
DNA of somatostatin gene incorporated into E. coli near the chromosome containing genes for coding the beta galactosidase done
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C)
Incorporation of DNA of HGH into plasmids of E. coli done
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D)
Incorporation of RNA of HGH into plasmids of E. coli done
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question_answer 6)
The viruses infect the host cells. By the induction of viruses the host cells produce the
A)
Antigens done
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B)
Oncogens done
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C)
Interferon done
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D)
Carcinogens done
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question_answer 7)
The interferon of other animals
A)
Cannot be used in human done
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B)
Can be used in human done
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C)
Can only be used in that particular animal done
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D)
[a] and [c] both done
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question_answer 8)
In human type(s) of interferon present is (are)
A)
Leucocytic done
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B)
Fibroblastic done
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C)
Immune interferon done
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D)
All of the above done
clear
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question_answer 9)
How many amino acids are present in the human insulin
A)
21 done
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B)
30 done
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C)
31 done
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D)
51 done
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question_answer 10)
The interferon which is synthesised by WBC is known as
A)
Fibroblastic interferon done
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B)
Immune interferon done
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C)
Leucocytic interferon done
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D)
None of the above done
clear
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question_answer 11)
The grafting principle depends upon the
A)
Close blood relationship done
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B)
Similar immune system done
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C)
Only genetic similarity is required done
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D)
Blood groups, immune system and genetic combination done
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question_answer 12)
Grafting between two members of same species is
A)
Allograft done
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B)
Autograft done
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C)
Xenograft done
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D)
None of the above done
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question_answer 13)
Grafting between two different species is
A)
Allograft done
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B)
Intergraft done
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C)
Xenograft done
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D)
Heterograft done
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question_answer 14)
Donor and recipient of the transplanting tissue is the same person. This type of grafting is known as
A)
Xenograft done
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B)
Autograft done
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C)
Self graft done
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D)
Holograft done
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question_answer 15)
Nobel prize to Kornberg and Ochoa was given for [DPMT 1977, 86; BHU 1986; AMU 1989; RPMT 2002]
A)
Artificial synthesis of genes done
clear
B)
Chemistry of DNA and RNA done
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C)
?One gene one enzyme' hypothesis done
clear
D)
Artificial synthesis of DNA done
clear
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question_answer 16)
Branch dealing with genetic engineering is [MP PMT 1993]
A)
Eugenics done
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B)
Euthenics done
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C)
Euphenics done
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D)
None of these done
clear
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question_answer 17)
?Tissue culture'' means [MP PMT 1993]
A)
Cultivation of tissue in laboratory through formation of new cells done
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B)
Introduction of new tissue in an animal body done
clear
C)
A technique for maintaining fragments of cells alive after their removal from an organism done
clear
D)
Maintaining tissue alive by immersing it partially in a nutrient fluid done
clear
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question_answer 18)
Genetic engineering means [CMC Vellore 1993]
A)
Manipulation of cell contents done
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B)
Test tube babies done
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C)
Manipulation of cytochromes done
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D)
Manipulation of genes done
clear
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question_answer 19)
Who among the following scientists is associated with the discoveries in genetic engineering [CBSE PMT 1993]
A)
Khorana done
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B)
Watson done
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C)
Crick done
clear
D)
Messelson done
clear
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question_answer 20)
Gene synthesis is related to [CPMT 1991; J&K CET 2005]
A)
V. Baer done
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B)
H.G. Khorana done
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C)
L. Pasteur done
clear
D)
C. Linnaeus done
clear
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question_answer 21)
Which one of the following techniques is employed in human genetic counselling [Kerala CET 2005]
A)
Serological technique done
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B)
Polyploidy done
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C)
Genetic engineering done
clear
D)
Amniocentesis done
clear
E)
Pedigree analysis done
clear
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question_answer 22)
The process of joining together different DNA fragments is often referred to as [MP PMT 1994]
A)
Transcription done
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B)
Cloning done
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C)
Gene splicing done
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D)
DNA amplification done
clear
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question_answer 23)
It is now possible to breed plants and animals with desired characters through [KCET 1994]
A)
Genetic engineering done
clear
B)
Chromosome engineering done
clear
C)
Ikebana technique done
clear
D)
Tissue culture done
clear
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question_answer 24)
Which of the following organelles is related with genetic engineering [CBSE PMT 1994; BVP 2004]
A)
Golgi apparatus done
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B)
Lysosomes done
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C)
Mitochondria done
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D)
Plasmids done
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question_answer 25)
DNA fingerprinting method is very useful for [MP PMT 1998]
A)
DNA tests for identity and relationships done
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B)
Forensic studies done
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C)
Polymorphism done
clear
D)
All of the above done
clear
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question_answer 26)
Tissue culture was launched by [MP PMT 1999]
A)
Harrison done
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B)
Carrel done
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C)
Mendel done
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D)
Khorana done
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question_answer 27)
Restriction endonuclease is used in [MP PMT 1997, 99, 2000]
A)
Genetic engineering done
clear
B)
Tissue culture done
clear
C)
Cell fractionation done
clear
D)
Regeneration of tissues done
clear
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question_answer 28)
The confirmatory test used to diagnose AIDS is [Kerala PMT 2004]
A)
ELISA done
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B)
Western blot done
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C)
ESR done
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D)
PCR done
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E)
None of these done
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question_answer 29)
Genetic drift operates only in [CBSE PMT 1998]
A)
Island populations done
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B)
Smaller populations done
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C)
Larger populations done
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D)
Mendelian populations done
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question_answer 30)
Recombinant DNA technology is related with [BHU 1999]
A)
C. Darwin done
clear
B)
Stanley Cohen done
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C)
Herbert Boyer done
clear
D)
Both [b] and [c] done
clear
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question_answer 31)
A distinct mechanism that usually involves a short segment of DNA with remarkable capacity to move from one location in a chromosome to another, this is called [BHU 1999]
A)
DNA replication done
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B)
DNA transposition done
clear
C)
DNA hybridization done
clear
D)
DNA recombination done
clear
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question_answer 32)
First cloned animal is [CBSE PMT 2000]
A)
Dog done
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B)
Molly done
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C)
Dolly sheep done
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D)
Polly sheep done
clear
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question_answer 33)
Genetically engineered human insulin is prepared by using [BVP 2000]
A)
E. coli done
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B)
Rhizopus done
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C)
Pseudomonas done
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D)
Yeast done
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question_answer 34)
The frequency of an allele in an isolated population may change due to [CBSE PMT 1992, 2001]
A)
Gene flow done
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B)
Mutation done
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C)
Genetic drift done
clear
D)
Natural selection done
clear
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question_answer 35)
ANDI is cloned [Kerala CET 2002]
A)
Sheep done
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B)
Bull done
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C)
Monkey done
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D)
Cat done
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question_answer 36)
Which of these is widely used in genetic engineering [CPMT 2003]
A)
Anopheles done
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B)
Dragon fly done
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C)
Dragon lizard done
clear
D)
Fruit fly done
clear
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question_answer 37)
The best HLA (human leucocyte antigen) match for transplant in order of preference is [Kerala CET 2005]
A)
Parent > sibling > twin > unrelated donor done
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B)
Sibling > twin > parent > unrelated donor done
clear
C)
Twin > sibling > parent > unrelated donor done
clear
D)
Twin > unrelated donor > parent > sibling done
clear
E)
Sibling > parent > twin > unrelated donor done
clear
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question_answer 38)
Production of a human protein in bacteria by genetic engineering is possible because [CBSE PMT 2003, 05]
A)
Bacterial cell can carry out the RNA splicing reactions done
clear
B)
The human chromosome can replicate bacterial cell done
clear
C)
The mechanism of gene regulation is identical in humans and bacteria done
clear
D)
The genetic code is universal done
clear
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question_answer 39)
Golden rice is a transgenic crop of the future with the following improved trait [CBSE PMT 2003]
A)
High lysine (essential amino acid) content done
clear
B)
Insect resistance done
clear
C)
High protein content done
clear
D)
High vitamin-A content done
clear
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question_answer 40)
The transfer of protein from electrophoretic gel to nitrocellulose membrane is known as [MP PMT 2003]
A)
Transferase done
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B)
Northern blotting done
clear
C)
Western blotting done
clear
D)
Southern blotting done
clear
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question_answer 41)
The term genetic engineering is used for [MP PMT 2003]
A)
Blotting technique done
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B)
RNA reaction technique done
clear
C)
Protein synthesis technique done
clear
D)
Recombinant DNA technique done
clear
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question_answer 42)
DNA fingerprinting refers to [CBSE PMT 2004]
A)
Techniques used for molecular analysis of different specimens of DNA done
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B)
Techniques used for identification of fingerprints of individuals done
clear
C)
Molecular analysis of profiles of DNA samples done
clear
D)
Analysis of DNA samples using imprinting devices done
clear
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question_answer 43)
Restriction endonucleases [CBSE PMT 2004]
A)
Are used for in uitro DNA synthesis done
clear
B)
Are synthesized by bacteria as part of defense mechanism done
clear
C)
Are present in mammalian cells for degradation of DNA when the cells dies done
clear
D)
Are used in genetic engineering for ligating two DNA molecules done
clear
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question_answer 44)
Restriction endonuclease, an enzyme used in Genetic Engineering is employed for [Kerala PMT 2004]
A)
Probing exons done
clear
B)
Cutting double stranded DNA done
clear
C)
Cutting single stranded DNA done
clear
D)
Join strands of DNA done
clear
E)
Copying DNA strands. done
clear
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question_answer 45)
Identify the plasmid [KCET 2004]
A)
AIU I done
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B)
Hind III done
clear
C)
Eco RI done
clear
D)
pBr 322. done
clear
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question_answer 46)
DNA finger printing technique was first developed by [KCET 2004]
A)
Jeffreys, Wilson and Thien done
clear
B)
Boysen and Jensen done
clear
C)
Scleiden and Schwann done
clear
D)
Edward and Steptoe done
clear
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question_answer 47)
Choose the correct statement with reference to ?Dolly? [Kerala CET 2005]
A)
She was created by taking nucleus from unfertilised egg done
clear
B)
She was created by taking nucleus from udder cell and cytoplasm from unfertilised egg done
clear
C)
She was created by taking cytoplasm from udder cells and nucleus from fertilised egg done
clear
D)
She was created in the test tube done
clear
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question_answer 48)
An example of gene therapy is [AIIMS 2004]
A)
Production of injectable Hepatitis B vaccine done
clear
B)
Production of vaccines in food crops like potatoes which can be eaten done
clear
C)
Introduction of gene for adenosine deaminase in persons suffering from Severe Combined Immuno-deficiency (SCID) done
clear
D)
Production of test tube babies by artificial insemination and implantation of fertilized eggs done
clear
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question_answer 49)
What is the first step in the Southern Blot technique [AIIMS 2004]
A)
Denaturation of DNA on the gel for hybridization with specific probe done
clear
B)
Production of a group of genetically identical cells done
clear
C)
Digestion of DNA by restriction enzyme done
clear
D)
Isolation of DNA from a nucleated cell such as the one from the scene of crime done
clear
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question_answer 50)
DNA repairing is done by [AFMC 2004; MP PMT 2005; Orissa JEE 2005]
A)
Ligase done
clear
B)
DNA polymerase III done
clear
C)
DNA polymerase II done
clear
D)
DNA polymerase I done
clear
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question_answer 51)
cDNA probes are copied from the messenger RNA molecules with the help of [AIIMS 2005; CPMT 2005]
A)
Restriction enzymes done
clear
B)
Reverse transcriptase done
clear
C)
DNA polymerase done
clear
D)
Adenosine diaminase done
clear
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question_answer 52)
Find the incorrect statement [Kerala CET 2005]
A)
Gene therapy is a genetic engineering technique used to treat diseases at molecular level by replacing defective genes with normal genes done
clear
B)
Calcitonin is a medically useful recombinant product in the treatment of infertility done
clear
C)
Bt toxin is a biodegradable insecticide obtained from Bacillus thuringiensis done
clear
D)
Trichoderma species is a biocontrol agent for fungal diseases of plants Totipotency is the potential ability of a cell to aevelop into a complete plant done
clear
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question_answer 53)
Which of the following is false for BT transgenic plant [BCECE 2005]
A)
Disease resistance done
clear
B)
Prepared by Bacillus thuringiensis done
clear
C)
It is recombinant type done
clear
D)
No such plant is known done
clear
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question_answer 54)
In recombination vector used is [BCECE 2005]
A)
Protein done
clear
B)
Agrobacterium tumefaciens done
clear
C)
Nucleic acid done
clear
D)
Cellulose done
clear
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question_answer 55)
A tumour inducing plasmid widely used in the production of transgenic plants is that of [AIIMS 2005]
A)
Escherichia coli done
clear
B)
Bacillus thuringiensis done
clear
C)
Staphylococcus aureus done
clear
D)
Agrobacterium tumefaciens done
clear
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question_answer 56)
Southern blotting is done for [Haryana 2005]
A)
DNA done
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B)
RNA done
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C)
mRNA done
clear
D)
Protein done
clear
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question_answer 57)
Crown gall disease in plants is caused by [BHU 2005]
A)
Ti-plasmid done
clear
B)
Pi-plasmid done
clear
C)
Bacteria done
clear
D)
Virus done
clear
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question_answer 58)
First biochemical to be produced commercially by microbial cloning and genetic engineering is [BHU 2005]
A)
Human insulin done
clear
B)
Penicillin done
clear
C)
Interferons done
clear
D)
Fertility factors done
clear
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question_answer 59)
In transgenics, expression of transgene in target tissue is determined by [CPMT 2005]
A)
Enhancer done
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B)
Promotor done
clear
C)
Transgene done
clear
D)
Reporter done
clear
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question_answer 60)
First hormone prepared by genetic engineering is [Manipal 2005]
A)
Oxytocin done
clear
B)
Somatotropin done
clear
C)
Adrenaline done
clear
D)
Insulin done
clear
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question_answer 61)
Polymerase chain reaction is most useful in [BHU 2005]
A)
DNA synthesis done
clear
B)
DNA amplification done
clear
C)
Protein synthesis done
clear
D)
Amino acid synthesis done
clear
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question_answer 62)
Common bacteria used in genetic engineering is [Manipal 2005]
A)
E. coli done
clear
B)
Diplococcus done
clear
C)
Rhizobium done
clear
D)
Spirillum done
clear
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question_answer 63)
Which one of the following pairs of terms/names mean one and the same thing [BHU 2003]
A)
Gene pool- Genome done
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B)
Codon - Gene done
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C)
Cistron -Triplet done
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D)
DNA fingerprinting-DNA profiling done
clear
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question_answer 64)
Which of the following discoveries resulted in a Nobel Prize [CBSE PMT 2003]
A)
Genetic engineering done
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B)
X-rays induce sex-linked recessive lethal mutations done
clear
C)
Cytoplasmic inheritance done
clear
D)
Recombination of linked genes done
clear
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